Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


suck pdf from google scholar
unlimited free pdf from europmc34883281    free
PDF from PMC    free
html from PMC    free
PDF vom PMID34883281  :  Publisher
PDF vom PMID34883281

suck abstract from ncbi

Nephropedia Template TP Text

Twit Text FOAVip

Twit Text #

English Wikipedia

  • Ferritin - from iron, through inflammation and autoimmunity, to COVID-19 #MMPMID34883281
  • Mahroum N; Alghory A; Kiyak Z; Alwani A; Seida R; Alrais M; Shoenfeld Y
  • J Autoimmun 2022[Jan]; 126 (ä): 102778 PMID34883281show ga
  • While it took decades to arrive to a conclusion that ferritin is more than an indicator of iron storage level, it took a short period of time through the COVID-19 pandemic to wonder what the reason behind high levels of ferritin in patients with severe COVID-19 might be. Unsurprisingly, acute phase reactant was not a satisfactory explanation. Moreover, the behavior of ferritin in patients with severe COVID-19 and the subsequent high mortality rates in patients with high ferritin levels necessitated further investigations to understand the role of ferritin in the diseases. Ferritin was initially described to accompany various acute infections, both viral and bacterial, indicating an acute response to inflammation. However, with the introduction of the hyperferritinemic syndrome connecting four severe pathological conditions such as adult-onset Still's disease, macrophage activation syndrome, catastrophic antiphospholipid syndrome, and septic shock added another aspect of ferritin where it could have a pathogenetic role rather than an extremely elevated protein only. In fact, suggesting that COVID-19 is a new member in the spectrum of hyperferritinemic syndrome besides the four mentioned conditions could hopefully direct further search on the pathogenetic role of ferritin. Doubtlessly, improving our understanding of those aspects of ferritin would enormously contribute to better coping with severe diseases in terms of treatment and prevention of complications. The origin, history, importance, and the advances of searching the role of ferritin in various pathological and clinical processes are presented hereby in our article. In addition, the implications of ferritin in COVID-19 are addressed.
  • |Acute-Phase Proteins[MESH]
  • |Autoimmune Diseases/blood[MESH]
  • |COVID-19/*blood[MESH]
  • |Communicable Diseases/blood[MESH]
  • |Ferritins/*blood[MESH]
  • |Humans[MESH]
  • |Hyperferritinemia[MESH]
  • |Inflammation[MESH]
  • |Iron[MESH]

  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    102778 ä.126 2022