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10.1016/j.jcv.2021.105045

http://scihub22266oqcxt.onion/10.1016/j.jcv.2021.105045
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34861600!8612762!34861600
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suck abstract from ncbi

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  • Confirmed circulation of SARS-CoV-2 in Irish blood donors prior to first national notification of infection #MMPMID34861600
  • Butler D; Coyne D; Pomeroy L; Williams P; Holder P; Carterson A; Field S; Waters A; O'Flaherty N
  • J Clin Virol 2022[Jan]; 146 (ä): 105045 PMID34861600show ga
  • INTRODUCTION: Blood donor studies offer a unique opportunity to screen healthy populations for the presence of antibodies to emerging infections. We describe the use of blood donor specimens to track the 'first-wave' of the COVID-19 pandemic in Ireland. METHODOLOGY: A random selection of donor samples received by the Irish Blood Transfusion Service (IBTS) between February and September 2020 (n = 8,509) were screened by multiple commercial SARs-CoV-2 antibody assays. The antibody detection rate was adjusted to the population to determine the SARS-CoV-2 seroprevalence in Ireland. RESULTS: SARS-CoV-2 antibody detection rose significantly during the first peak of COVID-19 infection, increasing from 0.3% in March, to 2.9% in April (p < 0.0001, The first SARS-CoV-2 antibody positive donor samples were collected on the 17th February 2020, 2 weeks prior to the first official notification. This is the earliest serological evidence of SARS-CoV-2 circulating in the Irish population. Our results also show a significantly higher antibody prevalence in the Capital city and in donors less than 40 years of age. CONCLUSIONS: The present study demonstrates evidence of SARS-CoV-2 antibody reactivity across all age groups and counties. The critical value of blood donor seroprevalence studies is apparent in this report which identified the earliest serological evidence of SARS-CoV-2 infection in Ireland, as well as documenting the evolution of COVID-19 pandemic in Ireland over time.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Antibodies, Viral[MESH]
  • |Blood Donors[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Seroepidemiologic Studies[MESH]


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  • suck abstract from ncbi

    105045 ä.146 2022