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10.1261/rna.078825.121 http://scihub22266oqcxt.onion/10.1261/rna.078825.121 34845084!8906546!34845084     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       RNA 2022 ; 28 (2): 239-249 Nephropedia Template TP {{tp|p=34845084|t=2022. Crystal structure of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) frameshifting pseudoknot |pdf=|usr=}}{{34845084}} gab.com Text Crystal structure of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) frameshifting pseudoknot JO: RNA http://www.kidney.de/pget.php?&tw=1&pmid=34845084 #FOAvip SARS-CoV-2 produces two long viral protein precursors from one open reading frame using a highly conserved RNA pseudoknot that enhances programmed -1 ribosomal frameshifting. The 1.3 A-resolution X-ray structure of the pseudoknot reveals three coaxially stacked helices buttressed by idiosyncratic base triples from loop residues. This structure represents a frameshift-stimulating state that must be deformed by the ribosome and exhibits base-triple-adjacent pockets that could be targeted by future small-molecule therapeutics. Twit Text FOAVip Crystal structure of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) frameshifting pseudoknot ????RNA http://www.kidney.de/pget.php?&tw=1&pmid=34845084 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34845084 #FOAvip English Wikipedia <ref>{{Cite pmid|34845084}}</ref> Crystal structure of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) frameshifting pseudoknot #MMPMID34845084 Jones CP; Ferre-D'Amare AR RNA 2022[Feb]; 28 (2): 239-249 PMID34845084show ga SARS-CoV-2 produces two long viral protein precursors from one open reading frame using a highly conserved RNA pseudoknot that enhances programmed -1 ribosomal frameshifting. The 1.3 A-resolution X-ray structure of the pseudoknot reveals three coaxially stacked helices buttressed by idiosyncratic base triples from loop residues. This structure represents a frameshift-stimulating state that must be deformed by the ribosome and exhibits base-triple-adjacent pockets that could be targeted by future small-molecule therapeutics. |*Frameshifting, Ribosomal[MESH] |*Nucleic Acid Conformation[MESH] |Codon, Terminator[MESH] |Crystallography, X-Ray[MESH] |Models, Molecular[MESH] |Mutation[MESH] |RNA, Viral/*chemistry/genetics[MESH]Crystal structure of the severe acute respiratory syndrome coronavirus(epmc).pdf DeepDyve Pubget Overpricing