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10.3390/v13112258

http://scihub22266oqcxt.onion/10.3390/v13112258
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34835064!8618713!34835064
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suck abstract from ncbi


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pmid34835064      Viruses 2021 ; 13 (11): ä
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  • CRISPR Screening: Molecular Tools for Studying Virus-Host Interactions #MMPMID34835064
  • Chulanov V; Kostyusheva A; Brezgin S; Ponomareva N; Gegechkori V; Volchkova E; Pimenov N; Kostyushev D
  • Viruses 2021[Nov]; 13 (11): ä PMID34835064show ga
  • CRISPR/Cas is a powerful tool for studying the role of genes in viral infections. The invention of CRISPR screening technologies has made it possible to untangle complex interactions between the host and viral agents. Moreover, whole-genome and pathway-specific CRISPR screens have facilitated identification of novel drug candidates for treating viral infections. In this review, we highlight recent developments in the fields of CRISPR/Cas with a focus on the use of CRISPR screens for studying viral infections and identifying new candidate genes to aid development of antivirals.
  • |*CRISPR-Cas Systems[MESH]
  • |*Genetic Techniques[MESH]
  • |Drug Discovery[MESH]
  • |Genome-Wide Association Study/*methods[MESH]
  • |High-Throughput Screening Assays/*methods[MESH]
  • |Host Microbial Interactions[MESH]
  • |Humans[MESH]
  • |Virus Diseases/*genetics/*virology[MESH]


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