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10.3390/jpm11111086

http://scihub22266oqcxt.onion/10.3390/jpm11111086
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34834437!8625038!34834437
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suck abstract from ncbi


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pmid34834437      J+Pers+Med 2021 ; 11 (11): ä
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  • Vaccinated Patients Admitted in ICU with Severe Pneumonia Due to SARS-CoV-2: A Multicenter Pilot Study #MMPMID34834437
  • Estella A; Canton ML; Munoz L; Higueras IR; Recuerda Nunez M; Tejero Aranguren J; Zaya B; Gomez C; Amaya R; Hurtado Martinez A; Del Valle Odero Bernal M; De la Fuente C; Alados JC; Garnacho-Montero J; On Behalf Of The Group Of Infectious Diseases Of The Andalusian Society Of Intensive Care And Coronary Units Samiuc
  • J Pers Med 2021[Oct]; 11 (11): ä PMID34834437show ga
  • Background: The aim of this study was to analyze the percentage of patients admitted to the ICU having received the vaccine against COVID-19, to describe the clinical profile of vaccinated patients admitted to the ICU, and to assess the humoral immune response to vaccination. Methods: In this multicenter prospective descriptive cohort study, consecutive critically ill patients with confirmed SARS-CoV-2 pneumonia who received at least one dose of the SARS-CoV-2 vaccine were included. The time of study was from 1 July to 10 August of 2021. Results: Of the 94 consecutive patients from seven Andalusian ICUs admitted during the time of study, 50 (53.2%) received at least one dose of anti SARS-CoV-2 vaccine. No patient was admitted having previously had SARS-CoV-2 infection. The B.1.617.2 (Delta) variant was the most frequently identified, in 80.76% of cases. Patients with a complete vaccination with non-optimal antibody levels were immunocompromised. Fifteen patients were admitted to the ICU with Acute Respiratory Distress Syndrome (ARDS) without having completed their vaccination; the clinical profile was younger and with less comorbidities compared to patients with full vaccination. There were no differences in severity of ARDS. Conclusions: Most of the patients who were admitted to the ICU having received a dose of the vaccine were not optimally vaccinated; fully vaccinated patients who did not obtain optimal serum antibody levels were patients considered immunocompromised.
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