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10.3390/biom11111624

http://scihub22266oqcxt.onion/10.3390/biom11111624
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34827621!8615708!34827621
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suck abstract from ncbi


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pmid34827621      Biomolecules 2021 ; 11 (11): ä
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  • The Effects of Vitamin D on Immune System and Inflammatory Diseases #MMPMID34827621
  • Ao T; Kikuta J; Ishii M
  • Biomolecules 2021[Nov]; 11 (11): ä PMID34827621show ga
  • Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin D receptor and 1alpha-hydroxylase. In vitro studies have shown that 1,25-dihydroxyvitamin D, the active form of vitamin D, has an anti-inflammatory effect. Recent epidemiological evidence has indicated a significant association between vitamin D deficiency and an increased incidence, or aggravation, of infectious diseases and inflammatory autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis. However, the impact of vitamin D on treatment and prevention, particularly in infectious diseases such as the 2019 coronavirus disease (COVID-19), remains controversial. Here, we review recent evidence associated with the relationship between vitamin D and inflammatory diseases and describe the underlying immunomodulatory effect of vitamin D.
  • |*COVID-19 Drug Treatment[MESH]
  • |Animals[MESH]
  • |Arthritis, Rheumatoid/drug therapy/prevention & control[MESH]
  • |Autoimmune Diseases/drug therapy[MESH]
  • |B-Lymphocytes/immunology[MESH]
  • |COVID-19/*prevention & control[MESH]
  • |Dendritic Cells/immunology[MESH]
  • |Disease Models, Animal[MESH]
  • |Humans[MESH]
  • |Immune System/*drug effects[MESH]
  • |Inflammation/*drug therapy[MESH]
  • |Influenza, Human/drug therapy/prevention & control[MESH]
  • |Lupus Erythematosus, Systemic/drug therapy/prevention & control[MESH]
  • |Macrophages/immunology[MESH]
  • |Mice[MESH]
  • |Monocytes/immunology[MESH]
  • |Multiple Sclerosis/drug therapy/prevention & control[MESH]
  • |Receptors, Calcitriol/genetics/physiology[MESH]
  • |T-Lymphocytes/immunology[MESH]
  • |Vitamin D Deficiency/complications[MESH]


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