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10.1080/14789450.2021.2010549

http://scihub22266oqcxt.onion/10.1080/14789450.2021.2010549
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34812694!ä!34812694

suck abstract from ncbi


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pmid34812694      Expert+Rev+Proteomics 2021 ; 18 (11): 925-938
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  • Human bronchial-pulmonary proteomics in coronavirus disease 2019 (COVID-19) pandemic: applications and implications #MMPMID34812694
  • Tan HW; Xu YM; Lau ATY
  • Expert Rev Proteomics 2021[Nov]; 18 (11): 925-938 PMID34812694show ga
  • INTRODUCTION: The outbreak of the newly discovered human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has disrupted the normal life of almost every civilization worldwide. Studies have shown that the coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 can affect multiple human organs and physiological systems, but the respiratory system remains the primary location for viral infection. AREAS COVERED: We summarize how omics technologies are used in SARS-CoV-2 research and specifically review the current knowledge of COVID-19 from the aspect of human bronchial-pulmonary proteomics. Also, knowledge gaps in COVID-19 that can be fulfilled by proteomics are discussed. EXPERT OPINION: Overall, human bronchial-pulmonary proteomics plays an important role in revealing the dynamics, functions, tropism, and pathogenicity of SARS-CoV-2, which is crucial for COVID-19 biomarker and therapeutic target discoveries. To more fully understand the impact of COVID-19, research from various angles using multi-omics approaches should also be conducted on the lungs as well as other organs.
  • |*Pandemics[MESH]
  • |*Proteomics[MESH]
  • |Animals[MESH]
  • |Bronchi/*metabolism[MESH]
  • |COVID-19/*metabolism/virology[MESH]
  • |Humans[MESH]
  • |Lung/*metabolism[MESH]
  • |Molecular Targeted Therapy[MESH]


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