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10.1093/ajcp/aqab187

http://scihub22266oqcxt.onion/10.1093/ajcp/aqab187
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34791032!8690000!34791032
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suck abstract from ncbi


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pmid34791032      Am+J+Clin+Pathol 2022 ; 157 (5): 758-766
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  • Detection of COVID-19 by Machine Learning Using Routine Laboratory Tests #MMPMID34791032
  • Cubukcu HC; Topcu DI; Bayraktar N; Gulsen M; Sari N; Arslan AH
  • Am J Clin Pathol 2022[May]; 157 (5): 758-766 PMID34791032show ga
  • OBJECTIVES: The present study aimed to develop a clinical decision support tool to assist coronavirus disease 2019 (COVID-19) diagnoses with machine learning (ML) models using routine laboratory test results. METHODS: We developed ML models using laboratory data (n = 1,391) composed of six clinical chemistry (CC) results, 14 CBC parameter results, and results of a severe acute respiratory syndrome coronavirus 2 real-time reverse transcription-polymerase chain reaction as a gold standard method. Four ML algorithms, including random forest (RF), gradient boosting (XGBoost), support vector machine (SVM), and logistic regression, were used to build eight ML models using CBC and a combination of CC and CBC parameters. Performance evaluation was conducted on the test data set and external validation data set from Brazil. RESULTS: The accuracy values of all models ranged from 74% to 91%. The RF model trained from CC and CBC analytes showed the best performance on the present study's data set (accuracy, 85.3%; sensitivity, 79.6%; specificity, 91.2%). The RF model trained from only CBC parameters detected COVID-19 cases with 82.8% accuracy. The best performance on the external validation data set belonged to the SVM model trained from CC and CBC parameters (accuracy, 91.18%; sensitivity, 100%; specificity, 84.21%). CONCLUSIONS: ML models presented in this study can be used as clinical decision support tools to contribute to physicians' clinical judgment for COVID-19 diagnoses.
  • |*COVID-19/diagnosis[MESH]
  • |Algorithms[MESH]
  • |Humans[MESH]
  • |Logistic Models[MESH]
  • |Machine Learning[MESH]


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