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10.1021/acsptsci.0c00163

http://scihub22266oqcxt.onion/10.1021/acsptsci.0c00163
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34778724!7671100!34778724
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suck abstract from ncbi


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pmid34778724      ACS+Pharmacol+Transl+Sci 2020 ; 3 (6): 1361-1370
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  • Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2 #MMPMID34778724
  • Liu K; Zou R; Cui W; Li M; Wang X; Dong J; Li H; Li H; Wang P; Shao X; Su W; Chan HCS; Li H; Yuan S
  • ACS Pharmacol Transl Sci 2020[Dec]; 3 (6): 1361-1370 PMID34778724show ga
  • The outbreak of COVID-19 by the end of 2019 has posed serious health threats to humanity and jeopardized the global economy. However, no effective drugs are available to treat COVID-19 currently and there is a great demand to fight against it. Here, we combined computational screening and an efficient cellular pseudotyped virus system, confirming that clinical HDAC inhibitors can efficiently prevent SARS-CoV-2 and potentially be used to fight against COVID-19.
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