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10.1007/s00403-021-02299-8

http://scihub22266oqcxt.onion/10.1007/s00403-021-02299-8
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34773138!8589097!34773138
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suck abstract from ncbi


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pmid34773138      Arch+Dermatol+Res 2022 ; 314 (9): 897-902
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  • Associations between onychomycosis and COVID-19 clinical outcomes: a retrospective cohort study from a US metropolitan center #MMPMID34773138
  • Rakita U; Kaundinya T; Guraya A; Nelson K; Maner B; Manjunath J; Schwartzman G; Lane B; Silverberg JI
  • Arch Dermatol Res 2022[Nov]; 314 (9): 897-902 PMID34773138show ga
  • Little is known about the relationship of COVID-19 outcomes with onychomycosis. We investigated the relationship of onychomycosis with COVID-19 outcomes. A retrospective cohort study was performed on SARS-CoV-2 positive adult outpatients or inpatients who had onychomycosis and other skin diseases. Overall, 430 adults were identified with SARS-CoV-2 and a skin disease, including 98 with diagnosed onychomycosis. In bivariable logistic regression models, onychomycosis was associated with increased hospitalization odds ratio(OR) [95% confidence interval (CI)]: 3.56 [2.18-5.80], initial inpatient vs. outpatient visits (OR [95% CI]: 2.24 [1.35-3.74]), use of oxygen therapy (OR [95% CI]: 2.77 [1.60-4.79]), severe-critical vs. asymptomatic-mild severity (OR [95% CI]: 2.28 [1.32-3.94]), and death (OR [95% CI]: 7.48 [1.83-30.47]) from COVID-19, but not prolonged hospitalization (OR [95% CI]: 1.03 [0.47-2.25]). In multivariable models adjusting for socio-demographics, comorbidities, and immunosuppressant medication use, the associations with onychomycosis remained significant for hospitalization, inpatient visits, oxygen therapy, severe-critical COVID-19. Onychomycosis was a significant independent risk factor for COVID-19 severity, hospitalization, and receiving supplemental oxygen therapy.
  • |*COVID-19/epidemiology/therapy[MESH]
  • |*Onychomycosis/epidemiology/therapy[MESH]
  • |Adult[MESH]
  • |Humans[MESH]
  • |Immunosuppressive Agents[MESH]
  • |Oxygen/therapeutic use[MESH]
  • |Retrospective Studies[MESH]


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