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10.4103/joacp.JOACP_562_20

http://scihub22266oqcxt.onion/10.4103/joacp.JOACP_562_20
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34759566!8562453!34759566
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suck abstract from ncbi


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pmid34759566      J+Anaesthesiol+Clin+Pharmacol 2021 ; 37 (3): 481-483
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  • Intravenous lidocaine infusion in a case of severe COVID-19 infection #MMPMID34759566
  • Rylova A; Chowdhury S; Amirfarzan H; Leissner KB; Schumann R
  • J Anaesthesiol Clin Pharmacol 2021[Jul]; 37 (3): 481-483 PMID34759566show ga
  • A subset of patients with COVID-19 develops a severe inflammatory response that may lead to respiratory and multiorgan failure. Effective treatment strategies to mitigate or interrupt this self-destructive inflammatory process are limited. The local anesthetic lidocaine has anti-inflammatory properties in addition to its analgesic, antiarrhythmic, and sedating effects that may be beneficial in critically ill COVID-19 patients. We report the case of a patient with COVID-19 induced severe respiratory distress who was intubated and received supportive treatment including proning and neuromuscular blockade. He developed a strong inflammatory response that we treated with an intermittent lidocaine infusion resulting in subsequent resolution. This case occurred prior to emerging data from a large dexamethasone use trial that demonstrated a survival benefit from its use in hospitalized COVID-19 patients. At the time, lidocaine was the only anti-inflammatory medication our patient received.
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