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10.1021/jacsau.1c00288 http://scihub22266oqcxt.onion/10.1021/jacsau.1c00288 34723258!8549057!34723258     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       JACS+Au 2021 ; 1 (10): 1541-1555 Nephropedia Template TP {{tp|p=34723258|t=2021. Understanding the Logistics for the Distribution of Heme in Cells |pdf=|usr=}}{{34723258}} gab.com Text Understanding the Logistics for the Distribution of Heme in Cells JO: JACS Au http://www.kidney.de/pget.php?&tw=1&pmid=34723258 #FOAvip Heme is essential for the survival of virtually all living systems-from bacteria, fungi, and yeast, through plants to animals. No eukaryote has been identified that can survive without heme. There are thousands of different proteins that require heme in order to function properly, and these are responsible for processes such as oxygen transport, electron transfer, oxidative stress response, respiration, and catalysis. Further to this, in the past few years, heme has been shown to have an important regulatory role in cells, in processes such as transcription, regulation of the circadian clock, and the gating of ion channels. To act in a regulatory capacity, heme needs to move from its place of synthesis (in mitochondria) to other locations in cells. But while there is detailed information on how the heme lifecycle begins (heme synthesis), and how it ends (heme degradation), what happens in between is largely a mystery. Here we summarize recent information on the quantification of heme in cells, and we present a discussion of a mechanistic framework that could meet the logistical challenge of heme distribution. Twit Text FOAVip Understanding the Logistics for the Distribution of Heme in Cells ????JACS Au http://www.kidney.de/pget.php?&tw=1&pmid=34723258 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34723258 #FOAvip English Wikipedia <ref>{{Cite pmid|34723258}}</ref> Understanding the Logistics for the Distribution of Heme in Cells #MMPMID34723258 Gallio AE; Fung SS; Cammack-Najera A; Hudson AJ; Raven EL JACS Au 2021[Oct]; 1 (10): 1541-1555 PMID34723258show ga Heme is essential for the survival of virtually all living systems-from bacteria, fungi, and yeast, through plants to animals. No eukaryote has been identified that can survive without heme. There are thousands of different proteins that require heme in order to function properly, and these are responsible for processes such as oxygen transport, electron transfer, oxidative stress response, respiration, and catalysis. Further to this, in the past few years, heme has been shown to have an important regulatory role in cells, in processes such as transcription, regulation of the circadian clock, and the gating of ion channels. To act in a regulatory capacity, heme needs to move from its place of synthesis (in mitochondria) to other locations in cells. But while there is detailed information on how the heme lifecycle begins (heme synthesis), and how it ends (heme degradation), what happens in between is largely a mystery. Here we summarize recent information on the quantification of heme in cells, and we present a discussion of a mechanistic framework that could meet the logistical challenge of heme distribution. äUnderstanding the Logistics for the Distribution of Heme in Cells (epmc).pdf DeepDyve Pubget Overpricing