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10.1016/j.jgar.2021.10.012

http://scihub22266oqcxt.onion/10.1016/j.jgar.2021.10.012
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34718203!8552635!34718203
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suck abstract from ncbi


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pmid34718203      J+Glob+Antimicrob+Resist 2021 ; 27 (ä): 267-272
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  • Repatriation of a patient with COVID-19 contributed to the importation of an emerging carbapenemase producer #MMPMID34718203
  • Moser AI; Campos-Madueno EI; Sendi P; Perreten V; Keller PM; Ramette A; Endimiani A
  • J Glob Antimicrob Resist 2021[Dec]; 27 (ä): 267-272 PMID34718203show ga
  • OBJECTIVES: Patients hospitalised abroad can become colonised with multidrug-resistant bacteria and import them to their home countries. In this study, we characterised an OXA-484 carbapenemase-producing Escherichia coli strain from a Swiss patient infected by SARS-CoV-2 and repatriated from India. METHODS: At admission to Switzerland (April 2021), the patient undertook a nasopharyngeal swab to search for SARS-CoV-2 and a rectal swab to detect multidrug-resistant bacteria. Both SARS-CoV-2 and E. coli isolates were whole-genome sequenced and analysed for phylogenetic relatedness. RESULTS: The patient was infected with the SARS-CoV-2 B.1.617.2 lineage (VOC Delta), a lineage that began to be reported across Switzerland at that time. He was also colonised with a sequence type 410 (ST410) E. coli strain (L3452210II) producing OXA-484, a single amino acid variant of OXA-181. The bla(OXA-484) gene was carried by a 51.5 kb IncX3 plasmid identical to those described in bla(OXA-181)-harbouring ST410 E. coli strains. Core genome analysis showed that L3452210II was identical (DeltaSNV
  • |*COVID-19[MESH]
  • |*Escherichia coli Infections[MESH]
  • |*Escherichia coli Proteins/genetics[MESH]
  • |Anti-Bacterial Agents[MESH]
  • |Bacterial Proteins[MESH]
  • |Escherichia coli/genetics[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Microbial Sensitivity Tests[MESH]
  • |Phylogeny[MESH]
  • |SARS-CoV-2[MESH]


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