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10.3390/nu13103304 http://scihub22266oqcxt.onion/10.3390/nu13103304 34684306!8541297!34684306     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\34684306.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nutrients 2021 ; 13 (10): ä Nephropedia Template TP {{tp|p=34684306|t=2021. Course and Survival of COVID-19 Patients with Comorbidities in Relation to the Trace Element Status at Hospital Admission |pdf=|usr=}}{{34684306}} gab.com Text Course and Survival of COVID-19 Patients with Comorbidities in Relation to the Trace Element Status at Hospital Admission JO: Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=34684306 #FOAvip Selenium (Se) and zinc (Zn) are essential trace elements needed for appropriate immune system responses, cell signalling and anti-viral defence. A cross-sectional observational study was conducted at two hospitals in Ghent, Belgium, to investigate whether Se and/or Zn deficiency upon hospital admission correlates to disease severity and mortality risk in COVID-19 patients with or without co-morbidities. Trace element concentrations along with additional biomarkers were determined in serum or plasma and associated to disease severity and outcome. An insufficient Se and/or Zn status upon hospital admission was associated with a higher mortality rate and a more severe disease course in the entire study group, especially in the senior population. In comparison to healthy European adults, the patients displayed strongly depressed total Se (mean +/- SD: 59.2 +/- 20.6 vs. 84.4 +/- 23.4 microg L(-1)) and SELENOP (mean +/- SD: 2.2 +/- 1.9 vs. 4.3 +/- 1.0 mg L(-1)) concentrations at hospital admission. Particularly strong associations were observed for death risk of cancer, diabetes and chronic cardiac disease patients with low Se status, and of diabetes and obese patients with Zn deficiency. A composite biomarker based on serum or plasma Se, SELENOP and Zn at hospital admission proved to be a reliable tool to predict severe COVID-19 course and death, or mild disease course. We conclude that trace element assessment at hospital admission may contribute to a better stratification of patients with COVID-19 and other similar infectious diseases, support clinical care, therapeutic interventions and adjuvant supplementation needs, and may prove of particular relevance for patients with relevant comorbidities. Twit Text FOAVip Course and Survival of COVID-19 Patients with Comorbidities in Relation to the Trace Element Status at Hospital Admission ????Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=34684306 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34684306 #FOAvip English Wikipedia <ref>{{Cite pmid|34684306}}</ref> Course and Survival of COVID-19 Patients with Comorbidities in Relation to the Trace Element Status at Hospital Admission #MMPMID34684306 Du Laing G; Petrovic M; Lachat C; De Boevre M; Klingenberg GJ; Sun Q; De Saeger S; De Clercq J; Ide L; Vandekerckhove L; Schomburg L Nutrients 2021[Sep]; 13 (10): ä PMID34684306show ga Selenium (Se) and zinc (Zn) are essential trace elements needed for appropriate immune system responses, cell signalling and anti-viral defence. A cross-sectional observational study was conducted at two hospitals in Ghent, Belgium, to investigate whether Se and/or Zn deficiency upon hospital admission correlates to disease severity and mortality risk in COVID-19 patients with or without co-morbidities. Trace element concentrations along with additional biomarkers were determined in serum or plasma and associated to disease severity and outcome. An insufficient Se and/or Zn status upon hospital admission was associated with a higher mortality rate and a more severe disease course in the entire study group, especially in the senior population. In comparison to healthy European adults, the patients displayed strongly depressed total Se (mean +/- SD: 59.2 +/- 20.6 vs. 84.4 +/- 23.4 microg L(-1)) and SELENOP (mean +/- SD: 2.2 +/- 1.9 vs. 4.3 +/- 1.0 mg L(-1)) concentrations at hospital admission. Particularly strong associations were observed for death risk of cancer, diabetes and chronic cardiac disease patients with low Se status, and of diabetes and obese patients with Zn deficiency. A composite biomarker based on serum or plasma Se, SELENOP and Zn at hospital admission proved to be a reliable tool to predict severe COVID-19 course and death, or mild disease course. We conclude that trace element assessment at hospital admission may contribute to a better stratification of patients with COVID-19 and other similar infectious diseases, support clinical care, therapeutic interventions and adjuvant supplementation needs, and may prove of particular relevance for patients with relevant comorbidities. |Aged[MESH] |Aged, 80 and over[MESH] |Belgium[MESH] |Biomarkers/blood[MESH] |COVID-19/*blood/*epidemiology[MESH] |Comorbidity[MESH] |Cross-Sectional Studies[MESH] |Disease Progression[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Male[MESH] |Malnutrition/blood/*epidemiology[MESH] |Middle Aged[MESH] |SARS-CoV-2[MESH] |Selenium/*blood[MESH] |Severity of Illness Index[MESH] |Survival Analysis[MESH] |Trace Elements/*blood[MESH]Course and Survival of COVID-19 Patients with Comorbidities in Relatio(epmc).pdf DeepDyve Pubget Overpricing