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10.1016/j.bcp.2021.114809 http://scihub22266oqcxt.onion/10.1016/j.bcp.2021.114809 34673016!ä!34673016 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\34673016.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Biochem+Pharmacol 2021 ; 193 (ä): 114809 Nephropedia Template TP {{tp|p=34673016|t=2021. Pathogenic mitochondrial dysfunction and metabolic abnormalities |pdf=|usr=}}{{34673016}} gab.com Text Pathogenic mitochondrial dysfunction and metabolic abnormalities JO: Biochem Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=34673016 #FOAvip Herein we trace links between biochemical pathways, pathogenesis, and metabolic diseases to set the stage for new therapeutic advances. Cellular and acellular microorganisms including bacteria and viruses are primary pathogenic drivers that cause disease. Missing from this statement are subcellular compartments, importantly mitochondria, which can be pathogenic by themselves, also serving as key metabolic disease intermediaries. The breakdown of food molecules provides chemical energy to power cellular processes, with mitochondria as powerhouses and ATP as the principal energy carrying molecule. Most animal cell ATP is produced by mitochondrial synthase; its central role in metabolism has been known for >80 years. Metabolic disorders involving many organ systems are prevalent in all age groups. Progressive pathogenic mitochondrial dysfunction is a hallmark of genetic mitochondrial diseases, the most common phenotypic expression of inherited metabolic disorders. Confluent genetic, metabolic, and mitochondrial axes surface in diabetes, heart failure, neurodegenerative disease, and even in the ongoing coronavirus pandemic. Twit Text FOAVip Pathogenic mitochondrial dysfunction and metabolic abnormalities ????Biochem Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=34673016 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34673016 #FOAvip English Wikipedia <ref>{{Cite pmid|34673016}}</ref> Pathogenic mitochondrial dysfunction and metabolic abnormalities #MMPMID34673016 Moos WH; Faller DV; Glavas IP; Harpp DN; Kamperi N; Kanara I; Kodukula K; Mavrakis AN; Pernokas J; Pernokas M; Pinkert CA; Powers WR; Steliou K; Tamvakopoulos C; Vavvas DG; Zamboni RJ; Sampani K Biochem Pharmacol 2021[Nov]; 193 (ä): 114809 PMID34673016show ga Herein we trace links between biochemical pathways, pathogenesis, and metabolic diseases to set the stage for new therapeutic advances. Cellular and acellular microorganisms including bacteria and viruses are primary pathogenic drivers that cause disease. Missing from this statement are subcellular compartments, importantly mitochondria, which can be pathogenic by themselves, also serving as key metabolic disease intermediaries. The breakdown of food molecules provides chemical energy to power cellular processes, with mitochondria as powerhouses and ATP as the principal energy carrying molecule. Most animal cell ATP is produced by mitochondrial synthase; its central role in metabolism has been known for >80 years. Metabolic disorders involving many organ systems are prevalent in all age groups. Progressive pathogenic mitochondrial dysfunction is a hallmark of genetic mitochondrial diseases, the most common phenotypic expression of inherited metabolic disorders. Confluent genetic, metabolic, and mitochondrial axes surface in diabetes, heart failure, neurodegenerative disease, and even in the ongoing coronavirus pandemic. |Animals[MESH] |COVID-19/*metabolism/therapy[MESH] |Diet, Healthy[MESH] |Energy Metabolism/physiology[MESH] |Humans[MESH] |Metabolic Diseases/*metabolism/therapy[MESH] |Mitochondria/*metabolism[MESH] |Mitochondrial Diseases/*metabolism/therapy[MESH] |Neurodegenerative Diseases/*metabolism/therapy[MESH]Pathogenic mitochondrial dysfunction and metabolic abnormalities (epmc).pdf DeepDyve Pubget Overpricing