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10.1080/08923973.2021.1988102 http://scihub22266oqcxt.onion/10.1080/08923973.2021.1988102 34647511!8544669!34647511     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunopharmacol+Immunotoxicol 2021 ; 43 (6): 633-643 Nephropedia Template TP {{tp|p=34647511|t=2021. Purinergic receptor ligands: the cytokine storm attenuators, potential therapeutic agents for the treatment of COVID-19 |pdf=|usr=}}{{34647511}} gab.com Text Purinergic receptor ligands: the cytokine storm attenuators, potential therapeutic agents for the treatment of COVID-19 JO: Immunopharmacol Immunotoxicol http://www.kidney.de/pget.php?&tw=1&pmid=34647511 #FOAvip The coronavirus disease-19 (COVID-19), at first, was reported in Wuhan, China, and then rapidly became pandemic throughout the world. Cytokine storm syndrome (CSS) in COVID-19 patients is associated with high levels of cytokines and chemokines that cause multiple organ failure, systemic inflammation, and hemodynamic instabilities. Acute respiratory distress syndrome (ARDS), a common complication of COVID-19, is a consequence of cytokine storm. In this regard, several drugs have been being investigated to suppress this inflammatory condition. Purinergic signaling receptors comprising of P1 adenosine and P2 purinoceptors play a critical role in inflammation. Therefore, activation or inhibition of some subtypes of these kinds of receptors is most likely to be beneficial to attenuate cytokine storm. This article summarizes suggested therapeutic drugs with potential anti-inflammatory effects through purinergic receptors. Twit Text FOAVip Purinergic receptor ligands: the cytokine storm attenuators, potential therapeutic agents for the treatment of COVID-19 ????Immunopharmacol Immunotoxicol http://www.kidney.de/pget.php?&tw=1&pmid=34647511 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34647511 #FOAvip English Wikipedia <ref>{{Cite pmid|34647511}}</ref> Purinergic receptor ligands: the cytokine storm attenuators, potential therapeutic agents for the treatment of COVID-19 #MMPMID34647511 Zarei M; Sahebi Vaighan N; Ziai SA Immunopharmacol Immunotoxicol 2021[Dec]; 43 (6): 633-643 PMID34647511show ga The coronavirus disease-19 (COVID-19), at first, was reported in Wuhan, China, and then rapidly became pandemic throughout the world. Cytokine storm syndrome (CSS) in COVID-19 patients is associated with high levels of cytokines and chemokines that cause multiple organ failure, systemic inflammation, and hemodynamic instabilities. Acute respiratory distress syndrome (ARDS), a common complication of COVID-19, is a consequence of cytokine storm. In this regard, several drugs have been being investigated to suppress this inflammatory condition. Purinergic signaling receptors comprising of P1 adenosine and P2 purinoceptors play a critical role in inflammation. Therefore, activation or inhibition of some subtypes of these kinds of receptors is most likely to be beneficial to attenuate cytokine storm. This article summarizes suggested therapeutic drugs with potential anti-inflammatory effects through purinergic receptors. |*COVID-19 Drug Treatment[MESH] |Animals[MESH] |Anti-Inflammatory Agents/adverse effects/*therapeutic use[MESH] |Biomarkers/blood[MESH] |COVID-19/blood/immunology/virology[MESH] |Cytokine Release Syndrome/blood/immunology/*prevention & control/virology[MESH] |Cytokines/*blood[MESH] |Host-Pathogen Interactions[MESH] |Humans[MESH] |Ligands[MESH] |Molecular Targeted Therapy[MESH] |Multiple Organ Failure/immunology/prevention & control/virology[MESH] |Purinergic Antagonists/adverse effects/*therapeutic use[MESH] |Receptors, Purinergic/*drug effects/metabolism[MESH] |SARS-CoV-2/*drug effects/immunology/pathogenicity[MESH]Purinergic receptor ligands: the cytokine storm attenuators, potential(epmc).pdf DeepDyve Pubget Overpricing