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10.1101/2021.10.04.21264434 http://scihub22266oqcxt.onion/10.1101/2021.10.04.21264434 34642700!8509101!34642700     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\34642700.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       medRxiv 2021 ; ä (ä): ä Nephropedia Template TP {{tp|p=34642700|t=2021. Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae |pdf=|usr=}}{{34642700}} gab.com Text Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae JO: medRxiv http://www.kidney.de/pget.php?&tw=1&pmid=34642700 #FOAvip Two years into the SARS-CoV-2 pandemic, the post-acute sequelae of infection are compounding the global health crisis. Often debilitating, these sequelae are clinically heterogeneous and of unknown molecular etiology. Here, a transcriptome-wide investigation of this new condition was performed in a large cohort of acutely infected patients followed clinically into the post-acute period. Gene expression signatures of post-acute sequelae were already present in whole blood during the acute phase of infection, with both innate and adaptive immune cells involved. Plasma cells stood out as driving at least two distinct clusters of sequelae, one largely dependent on circulating antibodies against the SARS-CoV-2 spike protein and the other antibody-independent. Altogether, multiple etiologies of post-acute sequelae were found concomitant with SARS-CoV-2 infection, directly linking the emergence of these sequelae with the host response to the virus. Twit Text FOAVip Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae ????medRxiv http://www.kidney.de/pget.php?&tw=1&pmid=34642700 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34642700 #FOAvip English Wikipedia <ref>{{Cite pmid|34642700}}</ref> Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae #MMPMID34642700 Thompson RC; Simons NW; Wilkins L; Cheng E; Del Valle DM; Hoffman GE; Fennessy B; Mouskas K; Francoeur NJ; Johnson JS; Lepow L; Le Berichel J; Chang C; Beckmann AG; Wang YC; Nie K; Zaki N; Tuballes K; Barcessat V; Cedillo MA; Huckins L; Roussos P; Marron TU; Glicksberg BS; Nadkarni G; Gonzalez-Kozlova E; Kim-Schulze S; Sebra R; Merad M; Gnjatic S; Schadt EE; Charney AW; Beckmann ND medRxiv 2021[Oct]; ä (ä): ä PMID34642700show ga Two years into the SARS-CoV-2 pandemic, the post-acute sequelae of infection are compounding the global health crisis. Often debilitating, these sequelae are clinically heterogeneous and of unknown molecular etiology. Here, a transcriptome-wide investigation of this new condition was performed in a large cohort of acutely infected patients followed clinically into the post-acute period. Gene expression signatures of post-acute sequelae were already present in whole blood during the acute phase of infection, with both innate and adaptive immune cells involved. Plasma cells stood out as driving at least two distinct clusters of sequelae, one largely dependent on circulating antibodies against the SARS-CoV-2 spike protein and the other antibody-independent. Altogether, multiple etiologies of post-acute sequelae were found concomitant with SARS-CoV-2 infection, directly linking the emergence of these sequelae with the host response to the virus. äAcute COVID-19 gene-expression profiles show multiple etiologies of lo(epmc).pdf DeepDyve Pubget Overpricing