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10.3390/jcm10194493 http://scihub22266oqcxt.onion/10.3390/jcm10194493 34640510!8509830!34640510     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Med 2021 ; 10 (19): ä Nephropedia Template TP {{tp|p=34640510|t=2021. Correlation between alpha1-Antitrypsin Deficiency and SARS-CoV-2 Infection: Epidemiological Data and Pathogenetic Hypotheses |pdf=|usr=}}{{34640510}} gab.com Text Correlation between alpha1-Antitrypsin Deficiency and SARS-CoV-2 Infection: Epidemiological Data and Pathogenetic Hypotheses JO: J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=34640510 #FOAvip The most common hereditary disorder in adults, alpha1-antitrypsin deficiency (AATD), is characterized by reduced plasma levels or the abnormal functioning of alpha1-antitrypsin (AAT), a major human blood serine protease inhibitor, which is encoded by the SERine Protein INhibitor-A1 (SERPINA1) gene and produced in the liver. Recently, it has been hypothesized that the geographic differences in COVID-19 infection and fatality rates may be partially explained by ethnic differences in SERPINA1 allele frequencies. In our review, we examined epidemiological data on the correlation between the distribution of AATD, SARS-CoV-2 infection, and COVID-19 mortality rates. Moreover, we described shared pathogenetic pathways that may provide a theoretical basis for our epidemiological findings. We also considered the potential use of AAT augmentation therapy in patients with COVID-19. Twit Text FOAVip Correlation between alpha1-Antitrypsin Deficiency and SARS-CoV-2 Infection: Epidemiological Data and Pathogenetic Hypotheses ????J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=34640510 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34640510 #FOAvip English Wikipedia <ref>{{Cite pmid|34640510}}</ref> Correlation between alpha1-Antitrypsin Deficiency and SARS-CoV-2 Infection: Epidemiological Data and Pathogenetic Hypotheses #MMPMID34640510 Vianello A; Guarnieri G; Braccioni F; Molena B; Lococo S; Achille A; Lionello F; Salviati L; Caminati M; Senna G J Clin Med 2021[Sep]; 10 (19): ä PMID34640510show ga The most common hereditary disorder in adults, alpha1-antitrypsin deficiency (AATD), is characterized by reduced plasma levels or the abnormal functioning of alpha1-antitrypsin (AAT), a major human blood serine protease inhibitor, which is encoded by the SERine Protein INhibitor-A1 (SERPINA1) gene and produced in the liver. Recently, it has been hypothesized that the geographic differences in COVID-19 infection and fatality rates may be partially explained by ethnic differences in SERPINA1 allele frequencies. In our review, we examined epidemiological data on the correlation between the distribution of AATD, SARS-CoV-2 infection, and COVID-19 mortality rates. Moreover, we described shared pathogenetic pathways that may provide a theoretical basis for our epidemiological findings. We also considered the potential use of AAT augmentation therapy in patients with COVID-19. äCorrelation between alpha1-Antitrypsin Deficiency and SARS-CoV-2 Infec(epmc).pdf DeepDyve Pubget Overpricing