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10.1093/infdis/jiab524 http://scihub22266oqcxt.onion/10.1093/infdis/jiab524 34636907!8549282!34636907     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Infect+Dis 2022 ; 225 (4): 578-586 Nephropedia Template TP {{tp|p=34636907|t=2022. Anti-SARS-CoV-2 IgA Identifies Asymptomatic Infection in First Responders |pdf=|usr=}}{{34636907}} gab.com Text Anti-SARS-CoV-2 IgA Identifies Asymptomatic Infection in First Responders JO: J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=34636907 #FOAvip BACKGROUND: Immunoglobulin A (IgA) is an important component of the early immune response to SARS-CoV-2. Prior serosurveys in high-risk groups employing IgG testing alone have provided discordant estimates. The potential added benefit of IgA in serosurveys has not been established. METHODS: Longitudinal serosurvey of first responders (police, emergency medical service providers, fire fighters, and other staff) employing 3 serologic tests (anti-spike IgA, anti-spike IgG, and anti-nucleocapsid IgG) correlated with surveys assessing occupational and nonoccupational risk, exposure to COVID-19, and illnesses consistent with COVID-19. RESULTS: Twelve percent of first responders in Colorado at baseline and 22% at follow-up were assessed as having SARS-CoV-2 infection. Five percent at baseline and 6% at follow-up were seropositive only for IgA. Among those IgA positive only at baseline, the majority (69%) had a positive antibody at follow-up; 45% of those infected at baseline and 33% at follow-up were asymptomatic. At all time points, the estimated cumulative incidence in our study was higher than that in the general population. CONCLUSIONS: First responders are at high risk of infection with SARS-CoV-2. IgA testing identified a significant portion of cases missed by IgG testing and its use as part of serologic surveys may improve retrospective identification of asymptomatic infection. Twit Text FOAVip Anti-SARS-CoV-2 IgA Identifies Asymptomatic Infection in First Responders ????J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=34636907 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34636907 #FOAvip English Wikipedia <ref>{{Cite pmid|34636907}}</ref> Anti-SARS-CoV-2 IgA Identifies Asymptomatic Infection in First Responders #MMPMID34636907 Montague BT; Wipperman MF; Hooper AT; Hamon SC; Crow R; Elemo F; Hersh L; Langdon S; Hamilton JD; O'Brien MP; Simoes EAF J Infect Dis 2022[Feb]; 225 (4): 578-586 PMID34636907show ga BACKGROUND: Immunoglobulin A (IgA) is an important component of the early immune response to SARS-CoV-2. Prior serosurveys in high-risk groups employing IgG testing alone have provided discordant estimates. The potential added benefit of IgA in serosurveys has not been established. METHODS: Longitudinal serosurvey of first responders (police, emergency medical service providers, fire fighters, and other staff) employing 3 serologic tests (anti-spike IgA, anti-spike IgG, and anti-nucleocapsid IgG) correlated with surveys assessing occupational and nonoccupational risk, exposure to COVID-19, and illnesses consistent with COVID-19. RESULTS: Twelve percent of first responders in Colorado at baseline and 22% at follow-up were assessed as having SARS-CoV-2 infection. Five percent at baseline and 6% at follow-up were seropositive only for IgA. Among those IgA positive only at baseline, the majority (69%) had a positive antibody at follow-up; 45% of those infected at baseline and 33% at follow-up were asymptomatic. At all time points, the estimated cumulative incidence in our study was higher than that in the general population. CONCLUSIONS: First responders are at high risk of infection with SARS-CoV-2. IgA testing identified a significant portion of cases missed by IgG testing and its use as part of serologic surveys may improve retrospective identification of asymptomatic infection. |*Asymptomatic Infections[MESH] |*COVID-19/diagnosis/immunology[MESH] |*Emergency Responders[MESH] |Antibodies, Viral/*analysis[MESH] |Humans[MESH] |Immunoglobulin A/*analysis[MESH] |Immunoglobulin G/analysis[MESH]Anti-SARS-CoV-2 IgA Identifies Asymptomatic Infection in First Respond(epmc).pdf DeepDyve Pubget Overpricing