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10.1042/CS20210577 http://scihub22266oqcxt.onion/10.1042/CS20210577 34623425!ä!34623425 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Sci+(Lond) 2021 ; 135 (19): 2217-2242 Nephropedia Template TP {{tp|p=34623425|t=2021. How dendritic cells sense and respond to viral infections |pdf=|usr=}}{{34623425}} gab.com Text How dendritic cells sense and respond to viral infections JO: Clin Sci (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=34623425 #FOAvip The ability of dendritic cells (DCs) to sense viral pathogens and orchestrate a proper immune response makes them one of the key players in antiviral immunity. Different DC subsets have complementing functions during viral infections, some specialize in antigen presentation and cross-presentation and others in the production of cytokines with antiviral activity, such as type I interferons. In this review, we summarize the latest updates concerning the role of DCs in viral infections, with particular focus on the complex interplay between DC subsets and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Despite being initiated by a vast array of immune receptors, DC-mediated antiviral responses often converge towards the same endpoint, that is the production of proinflammatory cytokines and the activation of an adaptive immune response. Nonetheless, the inherent migratory properties of DCs make them a double-edged sword and often viral recognition by DCs results in further viral dissemination. Here we illustrate these various aspects of the antiviral functions of DCs and also provide a brief overview of novel antiviral vaccination strategies based on DCs targeting. Twit Text FOAVip How dendritic cells sense and respond to viral infections ????Clin Sci (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=34623425 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34623425 #FOAvip English Wikipedia <ref>{{Cite pmid|34623425}}</ref> How dendritic cells sense and respond to viral infections #MMPMID34623425 Marongiu L; Valache M; Facchini FA; Granucci F Clin Sci (Lond) 2021[Oct]; 135 (19): 2217-2242 PMID34623425show ga The ability of dendritic cells (DCs) to sense viral pathogens and orchestrate a proper immune response makes them one of the key players in antiviral immunity. Different DC subsets have complementing functions during viral infections, some specialize in antigen presentation and cross-presentation and others in the production of cytokines with antiviral activity, such as type I interferons. In this review, we summarize the latest updates concerning the role of DCs in viral infections, with particular focus on the complex interplay between DC subsets and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Despite being initiated by a vast array of immune receptors, DC-mediated antiviral responses often converge towards the same endpoint, that is the production of proinflammatory cytokines and the activation of an adaptive immune response. Nonetheless, the inherent migratory properties of DCs make them a double-edged sword and often viral recognition by DCs results in further viral dissemination. Here we illustrate these various aspects of the antiviral functions of DCs and also provide a brief overview of novel antiviral vaccination strategies based on DCs targeting. |COVID-19/*virology[MESH] |Cytokines/immunology[MESH] |Dendritic Cells/immunology/*virology[MESH] |Humans[MESH] |Receptors, Pattern Recognition/*immunology[MESH] |SARS-CoV-2/*pathogenicity[MESH]How dendritic cells sense and respond to viral infections (epmc).pdf DeepDyve Pubget Overpricing