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10.1155/2021/2203636 http://scihub22266oqcxt.onion/10.1155/2021/2203636 34603483!8485143!34603483     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Comput+Math+Methods+Med 2021 ; 2021 (ä): 2203636 Nephropedia Template TP {{tp|p=34603483|t=2021. Identification of Novel COVID-19 Biomarkers by Multiple Feature Selection Strategies |pdf=|usr=}}{{34603483}} gab.com Text Identification of Novel COVID-19 Biomarkers by Multiple Feature Selection Strategies JO: Comput Math Methods Med http://www.kidney.de/pget.php?&tw=1&pmid=34603483 #FOAvip Coronavirus disease 2019 (COVID-19) arising from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a global pandemic since its first report in December 2019. So far, SARS-CoV-2 nucleic acid detection has been deemed as the golden standard of COVID-19 diagnosis. However, this detection method often leads to false negatives, thus triggering missed COVID-19 diagnosis. Therefore, it is urgent to find new biomarkers to increase the accuracy of COVID-19 diagnosis. To explore new biomarkers of COVID-19 in this study, expression profiles were firstly accessed from the GEO database. On this basis, 500 feature genes were screened by the minimum-redundancy maximum-relevancy (mRMR) feature selection method. Afterwards, the incremental feature selection (IFS) method was used to choose a classifier with the best performance from different feature gene-based support vector machine (SVM) classifiers. The corresponding 66 feature genes were set as the optimal feature genes. Lastly, the optimal feature genes were subjected to GO functional enrichment analysis, principal component analysis (PCA), and protein-protein interaction (PPI) network analysis. All in all, it was posited that the 66 feature genes could effectively classify positive and negative COVID-19 and work as new biomarkers of the disease. Twit Text FOAVip Identification of Novel COVID-19 Biomarkers by Multiple Feature Selection Strategies ????Comput Math Methods Med http://www.kidney.de/pget.php?&tw=1&pmid=34603483 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34603483 #FOAvip English Wikipedia <ref>{{Cite pmid|34603483}}</ref> Identification of Novel COVID-19 Biomarkers by Multiple Feature Selection Strategies #MMPMID34603483 Zhang S; Qu R; Wang P; Wang S Comput Math Methods Med 2021[]; 2021 (ä): 2203636 PMID34603483show ga Coronavirus disease 2019 (COVID-19) arising from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a global pandemic since its first report in December 2019. So far, SARS-CoV-2 nucleic acid detection has been deemed as the golden standard of COVID-19 diagnosis. However, this detection method often leads to false negatives, thus triggering missed COVID-19 diagnosis. Therefore, it is urgent to find new biomarkers to increase the accuracy of COVID-19 diagnosis. To explore new biomarkers of COVID-19 in this study, expression profiles were firstly accessed from the GEO database. On this basis, 500 feature genes were screened by the minimum-redundancy maximum-relevancy (mRMR) feature selection method. Afterwards, the incremental feature selection (IFS) method was used to choose a classifier with the best performance from different feature gene-based support vector machine (SVM) classifiers. The corresponding 66 feature genes were set as the optimal feature genes. Lastly, the optimal feature genes were subjected to GO functional enrichment analysis, principal component analysis (PCA), and protein-protein interaction (PPI) network analysis. All in all, it was posited that the 66 feature genes could effectively classify positive and negative COVID-19 and work as new biomarkers of the disease. |Algorithms[MESH] |Biomarkers/*metabolism[MESH] |COVID-19 Testing[MESH] |COVID-19/*genetics/*metabolism[MESH] |Computational Biology[MESH] |False Negative Reactions[MESH] |False Positive Reactions[MESH] |Gene Expression Profiling[MESH] |Humans[MESH] |Machine Learning[MESH] |Models, Statistical[MESH] |Principal Component Analysis[MESH] |Protein Interaction Mapping[MESH] |Research Design[MESH]Identification of Novel COVID-19 Biomarkers by Multiple Feature Select(epmc).pdf DeepDyve Pubget Overpricing