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10.1007/s13365-021-01015-6

http://scihub22266oqcxt.onion/10.1007/s13365-021-01015-6
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suck abstract from ncbi


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pmid34550544      J+Neurovirol 2021 ; 27 (5): 797-801
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  • A unique case of Miller Fisher-Guillain-Barre overlap syndrome in a liver transplant recipient #MMPMID34550544
  • Ramirez-Sanchez C; Syed R; Meier A; LaBuzetta JN; Hylton DJ; Taremi M
  • J Neurovirol 2021[Oct]; 27 (5): 797-801 PMID34550544show ga
  • Guillain-Barre syndrome (GBS) is an ascending demyelinating polyneuropathy often associated with recent infection. Miller Fisher syndrome represents a variant with predominant facial and cranial nerve involvement, although Miller Fisher and Guillain-Barre overlap syndromes can occur. Guillain-Barre spectrum syndromes have been thought to be rare among solid organ transplant recipients. We describe an immunocompromised patient with a liver transplant who presented with ophthalmoplegia and bulbar deficits. His symptoms rapidly progressed to a state of descending paralysis involving the diaphragm; he then developed acute respiratory failure and eventually developed quadriparesis. Electromyography and a nerve conduction study demonstrated a severe sensorimotor axonal polyneuropathy consistent with Miller Fisher variant Guillain-Barre syndrome. Despite several negative nasopharyngeal swabs for COVID-19 polymerase chain reaction, a serology for SARS-CoV-2 IgG was positive. He was diagnosed with Miller Fisher-Guillain-Barre overlap syndrome with rapid recovery following treatment with plasma exchange. Although Guillain-Barre is a rare complication in solid organ transplant recipients, this case highlights the importance of rapid diagnosis and treatment of neurologic complications in transplant patients. Furthermore, it demonstrates a possible case of neurological complications from COVID-19 infection.
  • |COVID-19/*complications[MESH]
  • |Guillain-Barre Syndrome/*immunology/therapy/*virology[MESH]
  • |Humans[MESH]
  • |Immunocompromised Host[MESH]
  • |Liver Transplantation[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Miller Fisher Syndrome/*immunology/therapy/*virology[MESH]
  • |Plasmapheresis[MESH]
  • |SARS-CoV-2[MESH]


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