Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


10.1038/s41392-021-00753-7

http://scihub22266oqcxt.onion/10.1038/s41392-021-00753-7
suck pdf from google scholar
34531370!8443960!34531370
unlimited free pdf from europmc34531370    free
PDF from PMC    free
html from PMC    free

suck abstract from ncbi


Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
pmid34531370      Signal+Transduct+Target+Ther 2021 ; 6 (1): 342
Nephropedia Template TP

gab.com Text

Twit Text FOAVip

Twit Text #

English Wikipedia


  • Single-cell immune profiling reveals distinct immune response in asymptomatic COVID-19 patients #MMPMID34531370
  • Zhao XN; You Y; Cui XM; Gao HX; Wang GL; Zhang SB; Yao L; Duan LJ; Zhu KL; Wang YL; Li L; Lu JH; Wang HB; Fan JF; Zheng HW; Dai EH; Tian LY; Ma MJ
  • Signal Transduct Target Ther 2021[Sep]; 6 (1): 342 PMID34531370show ga
  • While some individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) present mild-to-severe disease, many SARS-CoV-2-infected individuals are asymptomatic. We sought to identify the distinction of immune response between asymptomatic and moderate patients. We performed single-cell transcriptome and T-cell/B-cell receptor (TCR/BCR) sequencing in 37 longitudinal collected peripheral blood mononuclear cell samples from asymptomatic, moderate, and severe patients with healthy controls. Asymptomatic patients displayed increased CD56(bri)CD16(-) natural killer (NK) cells and upregulation of interferon-gamma in effector CD4(+) and CD8(+) T cells and NK cells. They showed more robust TCR clonal expansion, especially in effector CD4(+) T cells, but lack strong BCR clonal expansion compared to moderate patients. Moreover, asymptomatic patients have lower interferon-stimulated genes (ISGs) expression in general but large interpatient variability, whereas moderate patients showed various magnitude and temporal dynamics of the ISGs expression across multiple cell populations but lower than a patient with severe disease. Our data provide evidence of different immune signatures to SARS-CoV-2 in asymptomatic infections.
  • |*COVID-19/genetics/immunology[MESH]
  • |*Single-Cell Analysis[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Carrier State/*immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lymphocytes/*immunology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Receptors, Antigen, B-Cell/genetics/immunology[MESH]
  • |Receptors, Antigen, T-Cell/genetics/immunology[MESH]
  • |SARS-CoV-2/genetics/*immunology[MESH]


  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    Linkout box