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10.1016/j.bpa.2020.12.011 http://scihub22266oqcxt.onion/10.1016/j.bpa.2020.12.011 34511224!7831801!34511224     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34511224&cmd=llinks): Failed to open stream: HTTP request failed! 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COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment - A narrative review |pdf=|usr=}}{{34511224}} gab.com Text COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment - A narrative review JO: Best Pract Res Clin Anaesthesiol http://www.kidney.de/pget.php?&tw=1&pmid=34511224 #FOAvip Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two SARS-CoV-2 pandemic "waves," intensive care unit (ICU) specialists are treating a large number of COVID19-associated acute respiratory distress syndrome (ARDS) patients. From a pathophysiological perspective, prominent mechanisms of COVID19-associated ARDS (CARDS) include severe pulmonary infiltration/edema and inflammation leading to impaired alveolar homeostasis, alteration of pulmonary physiology resulting in pulmonary fibrosis, endothelial inflammation (endotheliitis), vascular thrombosis, and immune cell activation. Although the syndrome ARDS serves as an umbrella term, distinct, i.e., CARDS-specific pathomechanisms and comorbidities can be noted (e.g., virus-induced endotheliitis associated with thromboembolism) and some aspects of CARDS can be considered ARDS "atypical." Importantly, specific evidence-based medical interventions for CARDS (with the potential exception of corticosteroid use) are currently unavailable, limiting treatment efforts to mostly supportive ICU care. In this article, we will discuss the underlying pulmonary pathophysiology and the clinical management of CARDS. In addition, we will outline current and potential future treatment approaches. Twit Text FOAVip COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment - A narrative review ????Best Pract Res Clin Anaesthesiol http://www.kidney.de/pget.php?&tw=1&pmid=34511224 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34511224 #FOAvip English Wikipedia <ref>{{Cite pmid|34511224}}</ref> COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment - A narrative review #MMPMID34511224 Pfortmueller CA; Spinetti T; Urman RD; Luedi MM; Schefold JC Best Pract Res Clin Anaesthesiol 2021[Oct]; 35 (3): 351-368 PMID34511224show ga Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two SARS-CoV-2 pandemic "waves," intensive care unit (ICU) specialists are treating a large number of COVID19-associated acute respiratory distress syndrome (ARDS) patients. From a pathophysiological perspective, prominent mechanisms of COVID19-associated ARDS (CARDS) include severe pulmonary infiltration/edema and inflammation leading to impaired alveolar homeostasis, alteration of pulmonary physiology resulting in pulmonary fibrosis, endothelial inflammation (endotheliitis), vascular thrombosis, and immune cell activation. Although the syndrome ARDS serves as an umbrella term, distinct, i.e., CARDS-specific pathomechanisms and comorbidities can be noted (e.g., virus-induced endotheliitis associated with thromboembolism) and some aspects of CARDS can be considered ARDS "atypical." Importantly, specific evidence-based medical interventions for CARDS (with the potential exception of corticosteroid use) are currently unavailable, limiting treatment efforts to mostly supportive ICU care. In this article, we will discuss the underlying pulmonary pathophysiology and the clinical management of CARDS. In addition, we will outline current and potential future treatment approaches. |*Health Knowledge, Attitudes, Practice[MESH] |Adrenal Cortex Hormones/administration & dosage[MESH] |Anticoagulants/administration & dosage[MESH] |COVID-19/diagnosis/physiopathology/*therapy[MESH] |Critical Care/*standards/trends[MESH] |Humans[MESH] |Immunologic Factors/administration & dosage[MESH] |Intensive Care Units/*standards/trends[MESH] |Respiration, Artificial/standards/trends[MESH]COVID-19-associated acute respiratory distress syndrome (CARDS): Curre(epmc).pdf DeepDyve Pubget Overpricing