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10.1186/s12940-021-00784-1

http://scihub22266oqcxt.onion/10.1186/s12940-021-00784-1
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34488764!8420152!34488764
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suck abstract from ncbi


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pmid34488764      Environ+Health 2021 ; 20 (1): 101
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  • Impact of long-term exposure to PM(2 5) and temperature on coronavirus disease mortality: observed trends in France #MMPMID34488764
  • Tchicaya A; Lorentz N; Omrani H; de Lanchy G; Leduc K
  • Environ Health 2021[Sep]; 20 (1): 101 PMID34488764show ga
  • BACKGROUND: The outbreak of coronavirus disease (COVID-19) began in Wuhan, China in December 2019 and was declared a global pandemic on 11 March 2020. This study aimed to assess the effects of temperature and long-term exposure to air pollution on the COVID-19 mortality rate at the sub-national level in France. METHODS: This cross-sectional study considered different periods of the COVID-19 pandemic from May to December 2020. It included 96 departments (or NUTS 3) in mainland France. Data on long-term exposure to particulate matter (PM(2.5)), annual mean temperature, health services, health risk, and socio-spatial factors were used as covariates in negative binomial regression analysis to assess their influence on the COVID-19 mortality rate. All data were obtained from open-access sources. RESULTS: The cumulative COVID-19 mortality rate by department increased during the study period in metropolitan France-from 19.8/100,000 inhabitants (standard deviation (SD): 20.1) on 1 May 2020, to 65.4/100,000 inhabitants (SD: 39.4) on 31 December 2020. The rate was the highest in the departments where the annual average of long-term exposure to PM(2.5) was high. The negative binomial regression models showed that a 1 mug/m(3) increase in the annual average PM(2.5) concentration was associated with a statistically significant increase in the COVID-19 mortality rate, corresponding to 24.4%, 25.8%, 26.4%, 26.7%, 27.1%, 25.8%, and 15.1% in May, June, July, August, September, October, and November, respectively. This association was no longer significant on 1 and 31 December 2020. The association between temperature and the COVID-19 mortality rate was only significant on 1 November, 1 December, and 31 December 2020. An increase of 1 degrees C in the average temperature was associated with a decrease in the COVID-19-mortality rate, corresponding to 9.7%, 13.3%, and 14.5% on 1 November, 1 December, and 31 December 2020, respectively. CONCLUSION: This study found significant associations between the COVID-19 mortality rate and long-term exposure to air pollution and temperature. However, these associations tended to decrease with the persistence of the pandemic and massive spread of the disease across the entire country.
  • |Air Pollutants/*adverse effects[MESH]
  • |COVID-19/*mortality[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Environmental Exposure/*adverse effects/statistics & numerical data[MESH]
  • |France/epidemiology[MESH]
  • |Humans[MESH]
  • |Models, Statistical[MESH]
  • |Particulate Matter/*adverse effects[MESH]
  • |SARS-CoV-2[MESH]


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