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10.1016/j.jtbi.2021.110885 http://scihub22266oqcxt.onion/10.1016/j.jtbi.2021.110885 34478743!8406619!34478743     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Theor+Biol 2021 ; 530 (ä): 110885 Nephropedia Template TP {{tp|p=34478743|t=2021. Inverted repeats in coronavirus SARS-CoV-2 genome manifest the evolution events |pdf=|usr=}}{{34478743}} gab.com Text Inverted repeats in coronavirus SARS-CoV-2 genome manifest the evolution events JO: J Theor Biol http://www.kidney.de/pget.php?&tw=1&pmid=34478743 #FOAvip The world faces a great unforeseen challenge through the COVID-19 pandemic caused by coronavirus SARS-CoV-2. The virus genome structure and evolution are positioned front and center for further understanding insights on vaccine development, monitoring of transmission trajectories, and prevention of zoonotic infections of new coronaviruses. Of particular interest are genomic elements Inverse Repeats (IRs), which maintain genome stability, regulate gene expressions, and are the targets of mutations. However, little research attention is given to the IR content analysis in the SARS-CoV-2 genome. In this study, we propose a geometric analysis method and using the method to investigate the distributions of IRs in SARS-CoV-2 and its related coronavirus genomes. The method represents each genomic IR sequence pair as a single point and constructs the geometric shape of the genome using the IRs. Thus, the IR shape can be considered as the signature of the genome. The genomes of different coronaviruses are then compared using the constructed IR shapes. The results demonstrate that SARS-CoV-2 genome, specifically, has an abundance of IRs, and the IRs in coronavirus genomes show an increase during evolution events. Twit Text FOAVip Inverted repeats in coronavirus SARS-CoV-2 genome manifest the evolution events ????J Theor Biol http://www.kidney.de/pget.php?&tw=1&pmid=34478743 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34478743 #FOAvip English Wikipedia <ref>{{Cite pmid|34478743}}</ref> Inverted repeats in coronavirus SARS-CoV-2 genome manifest the evolution events #MMPMID34478743 Yin C; Yau SS J Theor Biol 2021[Dec]; 530 (ä): 110885 PMID34478743show ga The world faces a great unforeseen challenge through the COVID-19 pandemic caused by coronavirus SARS-CoV-2. The virus genome structure and evolution are positioned front and center for further understanding insights on vaccine development, monitoring of transmission trajectories, and prevention of zoonotic infections of new coronaviruses. Of particular interest are genomic elements Inverse Repeats (IRs), which maintain genome stability, regulate gene expressions, and are the targets of mutations. However, little research attention is given to the IR content analysis in the SARS-CoV-2 genome. In this study, we propose a geometric analysis method and using the method to investigate the distributions of IRs in SARS-CoV-2 and its related coronavirus genomes. The method represents each genomic IR sequence pair as a single point and constructs the geometric shape of the genome using the IRs. Thus, the IR shape can be considered as the signature of the genome. The genomes of different coronaviruses are then compared using the constructed IR shapes. The results demonstrate that SARS-CoV-2 genome, specifically, has an abundance of IRs, and the IRs in coronavirus genomes show an increase during evolution events. |*COVID-19[MESH] |*SARS-CoV-2[MESH] |Genome, Viral/genetics[MESH] |Genomics[MESH] |Humans[MESH] |Pandemics[MESH]Inverted repeats in coronavirus SARS-CoV-2 genome manifest the evoluti(epmc).pdf DeepDyve Pubget Overpricing