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10.1097/EDE.0000000000001415 http://scihub22266oqcxt.onion/10.1097/EDE.0000000000001415 34469363!8478108!34469363     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Epidemiology 2021 ; 32 (6): 820-828 Nephropedia Template TP {{tp|p=34469363|t=2021. Estimating Vaccine Efficacy Against Transmission via Effect on Viral Load |pdf=|usr=}}{{34469363}} gab.com Text Estimating Vaccine Efficacy Against Transmission via Effect on Viral Load JO: Epidemiology http://www.kidney.de/pget.php?&tw=1&pmid=34469363 #FOAvip Determining policies to end the SARS-CoV-2 pandemic will require an understanding of the efficacy and effectiveness (hereafter, efficacy) of vaccines. Beyond the efficacy against severe disease and symptomatic and asymptomatic infection, understanding vaccine efficacy against virus transmission, including efficacy against transmission of different viral variants, will help model epidemic trajectory and determine appropriate control measures. Recent studies have proposed using random virologic testing in individual randomized controlled trials to improve estimation of vaccine efficacy against infection. We propose to further use the viral load measures from these tests to estimate efficacy against transmission. This estimation requires a model of the relationship between viral load and transmissibility and assumptions about the vaccine effect on transmission and the progress of the epidemic. We describe these key assumptions, potential violations of them, and solutions that can be implemented to mitigate these violations. Assessing these assumptions and implementing this random sampling, with viral load measures, will enable better estimation of the crucial measure of vaccine efficacy against transmission. Twit Text FOAVip Estimating Vaccine Efficacy Against Transmission via Effect on Viral Load ????Epidemiology http://www.kidney.de/pget.php?&tw=1&pmid=34469363 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34469363 #FOAvip English Wikipedia <ref>{{Cite pmid|34469363}}</ref> Estimating Vaccine Efficacy Against Transmission via Effect on Viral Load #MMPMID34469363 Kennedy-Shaffer L; Kahn R; Lipsitch M Epidemiology 2021[Nov]; 32 (6): 820-828 PMID34469363show ga Determining policies to end the SARS-CoV-2 pandemic will require an understanding of the efficacy and effectiveness (hereafter, efficacy) of vaccines. Beyond the efficacy against severe disease and symptomatic and asymptomatic infection, understanding vaccine efficacy against virus transmission, including efficacy against transmission of different viral variants, will help model epidemic trajectory and determine appropriate control measures. Recent studies have proposed using random virologic testing in individual randomized controlled trials to improve estimation of vaccine efficacy against infection. We propose to further use the viral load measures from these tests to estimate efficacy against transmission. This estimation requires a model of the relationship between viral load and transmissibility and assumptions about the vaccine effect on transmission and the progress of the epidemic. We describe these key assumptions, potential violations of them, and solutions that can be implemented to mitigate these violations. Assessing these assumptions and implementing this random sampling, with viral load measures, will enable better estimation of the crucial measure of vaccine efficacy against transmission. |*COVID-19[MESH] |*Vaccines[MESH] |Humans[MESH] |Pandemics[MESH] |SARS-CoV-2[MESH]Estimating Vaccine Efficacy Against Transmission via Effect on Viral L(epmc).pdf DeepDyve Pubget Overpricing