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10.1002/iub.2552 http://scihub22266oqcxt.onion/10.1002/iub.2552 34467628!8652840!34467628     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34467628&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\34467628.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       IUBMB+Life 2021 ; 73 (11): 1278-1292 Nephropedia Template TP {{tp|p=34467628|t=2021. Mast cells: Therapeutic targets for COVID-19 and beyond |pdf=|usr=}}{{34467628}} gab.com Text Mast cells: Therapeutic targets for COVID-19 and beyond JO: IUBMB Life http://www.kidney.de/pget.php?&tw=1&pmid=34467628 #FOAvip Mast cells (MCs) are innate immune cells that widely distribute throughout all tissues and express a variety of cell surface receptors. Upon activation, MCs can rapidly release a diverse array of preformed mediators residing within their secretory granules and newly synthesize a broad spectrum of inflammatory and immunomodulatory mediators. These unique features of MCs enable them to act as sentinels in response to rapid changes within their microenvironment. There is increasing evidence now that MCs play prominent roles in other pathophysiological processes besides allergic inflammation. In this review, we highlight the recent findings on the emerging roles of MCs in the pathogenesis of coronavirus disease-2019 (COVID-19) and discuss the potential of MCs as novel therapeutic targets for COVID-19 and other non-allergic inflammatory diseases. Twit Text FOAVip Mast cells: Therapeutic targets for COVID-19 and beyond ????IUBMB Life http://www.kidney.de/pget.php?&tw=1&pmid=34467628 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34467628 #FOAvip English Wikipedia <ref>{{Cite pmid|34467628}}</ref> Mast cells: Therapeutic targets for COVID-19 and beyond #MMPMID34467628 Lam HY; Tergaonkar V; Kumar AP; Ahn KS IUBMB Life 2021[Nov]; 73 (11): 1278-1292 PMID34467628show ga Mast cells (MCs) are innate immune cells that widely distribute throughout all tissues and express a variety of cell surface receptors. Upon activation, MCs can rapidly release a diverse array of preformed mediators residing within their secretory granules and newly synthesize a broad spectrum of inflammatory and immunomodulatory mediators. These unique features of MCs enable them to act as sentinels in response to rapid changes within their microenvironment. There is increasing evidence now that MCs play prominent roles in other pathophysiological processes besides allergic inflammation. In this review, we highlight the recent findings on the emerging roles of MCs in the pathogenesis of coronavirus disease-2019 (COVID-19) and discuss the potential of MCs as novel therapeutic targets for COVID-19 and other non-allergic inflammatory diseases. |Animals[MESH] |COVID-19/immunology/pathology/*prevention & control[MESH] |Humans[MESH] |Immunity, Innate/*immunology[MESH] |Mast Cells/*immunology[MESH]Mast cells: Therapeutic targets for COVID-19 and beyond (epmc).pdf DeepDyve Pubget Overpricing