Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


10.1016/j.immuni.2021.08.013

http://scihub22266oqcxt.onion/10.1016/j.immuni.2021.08.013
suck pdf from google scholar
34464596!8367776!34464596
unlimited free pdf from europmc34464596    free
PDF from PMC    free
html from PMC    free

suck abstract from ncbi


Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
pmid34464596      Immunity 2021 ; 54 (9): 2159-2166.e6
Nephropedia Template TP

gab.com Text

Twit Text FOAVip

Twit Text #

English Wikipedia


  • A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants #MMPMID34464596
  • Schmitz AJ; Turner JS; Liu Z; Zhou JQ; Aziati ID; Chen RE; Joshi A; Bricker TL; Darling TL; Adelsberg DC; Altomare CG; Alsoussi WB; Case JB; VanBlargan LA; Lei T; Thapa M; Amanat F; Jeevan T; Fabrizio T; O'Halloran JA; Shi PY; Presti RM; Webby RJ; Krammer F; Whelan SPJ; Bajic G; Diamond MS; Boon ACM; Ellebedy AH
  • Immunity 2021[Sep]; 54 (9): 2159-2166.e6 PMID34464596show ga
  • The emergence of SARS-CoV-2 antigenic variants with increased transmissibility is a public health threat. Some variants show substantial resistance to neutralization by SARS-CoV-2 infection- or vaccination-induced antibodies. Here, we analyzed receptor binding domain-binding monoclonal antibodies derived from SARS-CoV-2 mRNA vaccine-elicited germinal center B cells for neutralizing activity against the WA1/2020 D614G SARS-CoV-2 strain and variants of concern. Of five monoclonal antibodies that potently neutralized the WA1/2020 D614G strain, all retained neutralizing capacity against the B.1.617.2 variant, four also neutralized the B.1.1.7 variant, and only one, 2C08, also neutralized the B.1.351 and B.1.1.28 variants. 2C08 reduced lung viral load and morbidity in hamsters challenged with the WA1/2020 D614G, B.1.351, or B.1.617.2 strains. Clonal analysis identified 2C08-like public clonotypes among B cells responding to SARS-CoV-2 infection or vaccination in 41 out of 181 individuals. Thus, 2C08-like antibodies can be induced by SARS-CoV-2 vaccines and mitigate resistance by circulating variants of concern.
  • |Animals[MESH]
  • |Antibodies, Monoclonal/*metabolism[MESH]
  • |Antibodies, Neutralizing/*metabolism[MESH]
  • |Antibodies, Viral/*metabolism[MESH]
  • |B-Lymphocytes/*immunology[MESH]
  • |COVID-19 Vaccines/*immunology[MESH]
  • |COVID-19/*immunology[MESH]
  • |Cells, Cultured[MESH]
  • |Clone Cells[MESH]
  • |Cricetinae[MESH]
  • |Disease Models, Animal[MESH]
  • |Germinal Center/*immunology[MESH]
  • |Humans[MESH]
  • |Lung/*virology[MESH]
  • |Neutralization Tests[MESH]
  • |SARS-CoV-2/*physiology[MESH]
  • |Spike Glycoprotein, Coronavirus/immunology[MESH]
  • |Vaccination[MESH]


  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    Linkout box