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10.1111/ane.13525

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34459497!8652819!34459497
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suck abstract from ncbi


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pmid34459497      Acta+Neurol+Scand 2021 ; 144 (6): 706-716
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  • An Internet-based study on the impact of COVID-19 pandemic-related lockdown on migraine in India #MMPMID34459497
  • Chowdhury D; Krishnan A; Duggal A; Datta D; Mundra A; Deorari V; Tomar A; Koul A
  • Acta Neurol Scand 2021[Dec]; 144 (6): 706-716 PMID34459497show ga
  • OBJECTIVES: To assess the impact of lockdown during the COVID-19 pandemic on migraine patients in India on disease activity, healthcare accessibility, and quality of life (QoL). MATERIALS & METHODS: This internet-based survey study using a structured questionnaire was conducted from 27th April to 31st July 2020. Previous physician-diagnosed migraine patients or those fulfilling any two of three clinical features (limitation of activities for >1 day, associated nausea or vomiting, and photophobia or phonophobia) were diagnosed as migraine patients. QoL was captured using a Likert scale and determinants of poor QoL were identified by logistic regression. RESULTS: A total of 4078 persons completed the full survey out of which 984 (24.1%) had migraine (mean age 35.3 +/-11.2). Compared to pre-lockdown, 51.3% of migraineurs reported worsening of their headaches in terms of increased attack frequency (95.6%), increased headache days (95%), increased attack duration (89.9%) and increased headache severity (88.1%). The worsening was attributed to anxiety due to the pandemic (79.7%), inability or difficulty to access healthcare (48.4%) and migraine medicines (48.9%), and financial worries (60.9%). 26.8% of migraineurs reported poor QoL compared to 7.37% of non-migraineurs [p<0.0001]. Migraine affected QoL in 61.4% of migraineurs. The predictors of poor QoL on logistic regression included worsening migraine during the lockdown (AOR 4.150; CI 2.704- 6.369) and difficulty accessing migraine medicines (AOR 4.549; CI 3.041- 6.805). Employment as an essential COVID-19 worker (AOR 0.623; CI 0.409- 0.950) protected against poor QoL. CONCLUSIONS: COVID-19 pandemic-related lockdown greatly impacted migraine patients in India which significantly reduced their QoL.
  • |*COVID-19[MESH]
  • |*Migraine Disorders/epidemiology[MESH]
  • |Adult[MESH]
  • |Communicable Disease Control[MESH]
  • |Humans[MESH]
  • |India/epidemiology[MESH]
  • |Internet[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Quality of Life[MESH]
  • |SARS-CoV-2[MESH]


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