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10.3389/fmed.2021.708284

http://scihub22266oqcxt.onion/10.3389/fmed.2021.708284
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34458285!8385714!34458285
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suck abstract from ncbi


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pmid34458285      Front+Med+(Lausanne) 2021 ; 8 (ä): 708284
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  • Case Report: Management of Malignancy-Exacerbated Pemphigus Vulgaris During COVID-19 Pandemic #MMPMID34458285
  • Corra A; Cammelli F; Quintarelli L; Barbato G; Le Rose O; Salemme A; Di Zenzo G; Coratti F; Verdelli A; Aimo C; Mariotti EB; Bianchi B; Cianchi F; Caproni M
  • Front Med (Lausanne) 2021[]; 8 (ä): 708284 PMID34458285show ga
  • Pemphigus vulgaris is an intraepidermal autoimmune mucocutaneous blistering disease whose etiopathogenesis includes various trigger factors, i.e., drugs and malignancies. We present a case of malignancy-exacerbated pemphigus vulgaris which required a careful diagnostic process in order to rule out paraneoplastic pemphigus, along with the challenges posed by the need of treating both cutaneous and oncologic diseases. Possible post-operative complications post-poned the start of first-line immunosuppressive treatment of pemphigus. Moreover, the infective risks had to be minimized during the peak of the COVID-19 pandemic in Italy. Intravenous immunoglobulins were chosen as "bridge" therapy before the tumor surgical excision, followed by rituximab in post-operative phase.
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