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10.1016/j.bioorg.2021.105274 http://scihub22266oqcxt.onion/10.1016/j.bioorg.2021.105274 34455301!8373853!34455301     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34455301&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Bioorg+Chem 2021 ; 116 (?): 105274 Nephropedia Template TP {{tp|p=34455301|t=2021. Screening out anti-inflammatory or anti-viral targets in Xuanfei Baidu Tang through a new technique of reverse finding target |pdf=|usr=}}{{34455301}} gab.com Text Screening out anti-inflammatory or anti-viral targets in Xuanfei Baidu Tang through a new technique of reverse finding target JO: Bioorg Chem http://www.kidney.de/pget.php?&tw=1&pmid=34455301 #FOAvip Traditional Chinese herbal compound prescription in Xuanfei Baidu Tang (XBT) has obvious effects in the treatment of COVID-19. However, its effective compounds and targets for the treatment of COVID-19 remain unclear. Computer-Aided Drug Design is used to virtually screen out the anti-inflammatory or anti-viral compounds in XBT, and predict the potential targets by Discovery Studio 2020. Then, we searched for COVID-19 targets using Genecards databases and Protein Data Bank (PDB) databases and compared them to identify targets that were common to both. Finally, the target we screened out is: TP53 (Tumor Protein P53). This article also shows that XBT in the treatment of COVID-19 works in a multi-link and overall synergistic manner. Our results will help to design the new drugs for COVID-19. Twit Text FOAVip Screening out anti-inflammatory or anti-viral targets in Xuanfei Baidu Tang through a new technique of reverse finding target ????Bioorg Chem http://www.kidney.de/pget.php?&tw=1&pmid=34455301 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34455301 #FOAvip English Wikipedia <ref>{{Cite pmid|34455301}}</ref> Screening out anti-inflammatory or anti-viral targets in Xuanfei Baidu Tang through a new technique of reverse finding target #MMPMID34455301 Wang Z; Zhang J; Zhan J; Gao H Bioorg Chem 2021[Nov]; 116 (?): 105274 PMID34455301show ga Traditional Chinese herbal compound prescription in Xuanfei Baidu Tang (XBT) has obvious effects in the treatment of COVID-19. However, its effective compounds and targets for the treatment of COVID-19 remain unclear. Computer-Aided Drug Design is used to virtually screen out the anti-inflammatory or anti-viral compounds in XBT, and predict the potential targets by Discovery Studio 2020. Then, we searched for COVID-19 targets using Genecards databases and Protein Data Bank (PDB) databases and compared them to identify targets that were common to both. Finally, the target we screened out is: TP53 (Tumor Protein P53). This article also shows that XBT in the treatment of COVID-19 works in a multi-link and overall synergistic manner. Our results will help to design the new drugs for COVID-19. |*COVID-19 Drug Treatment[MESH] |Anti-Inflammatory Agents, Non-Steroidal/chemistry/*pharmacology[MESH] |Antiviral Agents/chemistry/*pharmacology[MESH] |Drug Evaluation, Preclinical[MESH] |Drugs, Chinese Herbal/chemistry/*pharmacology[MESH] |Humans[MESH] |Medicine, Chinese Traditional[MESH] |Molecular Structure[MESH] |SARS-CoV-2/*drug effects/metabolism[MESH]Screening out anti-inflammatory or anti-viral targets in Xuanfei Baidu(epmc).pdf DeepDyve Pubget Overpricing