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10.1002/jmv.27301

http://scihub22266oqcxt.onion/10.1002/jmv.27301
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34449896!8662249!34449896
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suck abstract from ncbi

pmid34449896      J+Med+Virol 2022 ; 94 (1): 229-239
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  • Prevalence and clinical outcomes of pleural effusion in COVID-19 patients: A systematic review and meta-analysis #MMPMID34449896
  • Rathore SS; Hussain N; Manju AH; Wen Q; Tousif S; Avendano-Capriles CA; Hernandez-Woodbine MJ; Rojas GA; Vatsavayi P; Tera CR; Ali MA; Singh R; Saleemi S; Patel DM
  • J Med Virol 2022[Jan]; 94 (1): 229-239 PMID34449896show ga
  • Observational studies indicate that pleural effusion has an association with risk and the clinical prognosis of COVID-19 disease; however, the available literature on this area is inconsistent. The objective of this systematic review and meta-analysis is to evaluate the correlation between COVID-19 disease and pleural effusion. A rigorous literature search was conducted using multiple databases. All eligible observational studies were included from around the globe. The pooled prevalence and associated 95% confidence interval (CI) were calculated using the random effect model. Mantel-Haenszel odds ratios were produced to report overall effect size using random effect models for severity and mortality outcomes. Funnel plots, Egger regression tests, and Begg-Mazumdar's rank correlation test were used to appraise publication bias. Data from 23 studies including 6234 COVID-19 patients was obtained. The overall prevalence of pleural effusion in COVID-19 patients was 9.55% (95% CI, I(2 ) = 92%). Our findings also indicated that the presence of pleural effusions associated with increased risk of severity of disease(OR = 5.08, 95% CI 3.14-8.22, I(2 ) = 77.4%) and mortality due to illness(OR = 4.53, 95% CI 2.16-9.49, I(2 ) = 66%) compared with patients without pleural effusion. Sensitivity analyses illustrated a similar effect size while decreasing the heterogeneity. No significant publication bias was evident in the meta-analysis. The presence of pleural effusion can assist as a prognostic factor to evaluate the risk of worse outcomes in COVID-19 patients hence, it is recommended that hospitalized COVID-19 patients with pleural effusion should be managed on an early basis.
  • |COVID-19/*complications/diagnosis/mortality[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Pleural Effusion/*complications/diagnosis/epidemiology[MESH]
  • |Prevalence[MESH]
  • |Prognosis[MESH]


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