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10.1111/bjh.17804

http://scihub22266oqcxt.onion/10.1111/bjh.17804
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34448203!8652653!34448203
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suck abstract from ncbi


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pmid34448203      Br+J+Haematol 2022 ; 196 (2): 351-355
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  • A real-world study of immune thrombocytopenia management during the COVID-19 pandemic in the UK #MMPMID34448203
  • Rampotas A; Watson E; Burton K; Hill QA; Pavord S
  • Br J Haematol 2022[Jan]; 196 (2): 351-355 PMID34448203show ga
  • The COVID-19 pandemic has created many challenges in the management of immune thrombocytopenic purpura (ITP). The recommendation for avoidance of steroids by WHO led to the off-licence use, supported by NHS England, of thrombopoietin mimetics (TPO-RA) for newly diagnosed or relapsed ITP. This is a real-world prospective study which investigated the treatment patterns and outcomes in this setting. Twenty-four hospitals across the UK submitted 343 cases. Corticosteroids remain the mainstay of ITP treatment, but TPO-RAs were more effective. Incidental COVID-19 infection was identified in a significant number of patients (9.5%), while 14 cases were thought to be secondary to COVID-19 vaccination.
  • |*Pandemics[MESH]
  • |Adolescent[MESH]
  • |Adrenal Cortex Hormones/administration & dosage/adverse effects/therapeutic use[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Autoimmune Diseases/complications[MESH]
  • |COVID-19 Vaccines/adverse effects[MESH]
  • |COVID-19/blood/*epidemiology[MESH]
  • |Combined Modality Therapy[MESH]
  • |Comorbidity[MESH]
  • |Connective Tissue Diseases/complications[MESH]
  • |Contraindications, Drug[MESH]
  • |Disease Management[MESH]
  • |Female[MESH]
  • |Hemorrhage/epidemiology/etiology[MESH]
  • |Hospitals, District/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Immunoglobulins, Intravenous/therapeutic use[MESH]
  • |Immunosuppressive Agents/therapeutic use[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neoplasms/complications[MESH]
  • |Off-Label Use[MESH]
  • |Platelet Transfusion[MESH]
  • |Prospective Studies[MESH]
  • |Purpura, Thrombocytopenic, Idiopathic/drug therapy/epidemiology/etiology/*therapy[MESH]
  • |Tertiary Care Centers/statistics & numerical data[MESH]
  • |Thromboembolism/epidemiology/etiology[MESH]
  • |Thrombopoietin/agonists[MESH]
  • |Tranexamic Acid/therapeutic use[MESH]
  • |Treatment Outcome[MESH]
  • |United Kingdom/epidemiology[MESH]


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