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10.1136/bcr-2021-244168

http://scihub22266oqcxt.onion/10.1136/bcr-2021-244168
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34446515!8395362!34446515
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suck abstract from ncbi


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pmid34446515      BMJ+Case+Rep 2021 ; 14 (8): ä
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  • Liver transplantation for post-COVID-19 sclerosing cholangitis #MMPMID34446515
  • Lee A; Wein AN; Doyle MBM; Chapman WC
  • BMJ Case Rep 2021[Aug]; 14 (8): ä PMID34446515show ga
  • Since identified in December 2019, COVID-19 has remained a pandemic across the globe. Although primarily a respiratory illness, the impact of COVID-19 on other end organs has been increasingly identified. The effect of COVID-19 on the liver has yet to be completely understood. We describe a case of COVID-19 leading to end-stage cholangiopathy and deceased donor liver transplantation (LT). A 64-year-old man with no underlying respiratory or liver disease presented with acute respiratory distress secondary to COVID-19 pneumonia requiring intubation. Several months after resolution of his respiratory symptoms, he developed transaminitis, worsening jaundice, abdominal pain and dark-coloured urine. Hepatic function remained severely impaired warranting LT 259 days following his initial COVID-19 diagnosis. Explant pathology demonstrated diffuse hepatic injury, onion skinning of the bile ducts and bile duct loss in scattered portal tracts. As more patients develop COVID-19-related complications, we suggest LT as an option for COVID-19-related end-stage liver disease.
  • |*COVID-19[MESH]
  • |*Cholangitis, Sclerosing/complications/surgery[MESH]
  • |*Liver Transplantation[MESH]
  • |COVID-19 Testing[MESH]
  • |Humans[MESH]
  • |Living Donors[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]


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