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10.1080/1547691X.2021.1959677 http://scihub22266oqcxt.onion/10.1080/1547691X.2021.1959677 34436982!9885815!34436982     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunotoxicol 2021 ; 18 (1): 93-104 Nephropedia Template TP {{tp|p=34436982|t=2021. Dietary advanced glycation end-products elicit toxicological effects by disrupting gut microbiome and immune homeostasis |pdf=|usr=}}{{34436982}} gab.com Text Dietary advanced glycation end-products elicit toxicological effects by disrupting gut microbiome and immune homeostasis JO: J Immunotoxicol http://www.kidney.de/pget.php?&tw=1&pmid=34436982 #FOAvip The aging immune system is characterized by a low-grade chronic systemic inflammatory state ("inflammaging") marked by elevated serum levels of inflammatory molecules such as interleukin (IL)-6 and C-reactive protein (CRP). These inflammatory markers were also reported to be strong predictors for the development/severity of Type 2 diabetes, obesity, and COVID-19. The levels of these markers have been positively associated with those of advanced glycation end-products (AGEs) generated via non-enzymatic glycation and oxidation of proteins and lipids during normal aging and metabolism. Based on the above observations, it is clinically important to elucidate how dietary AGEs modulate inflammation and might thus increase the risk for aging-exacerbated diseases. The present narrative review discusses the potential pro-inflammatory properties of dietary AGEs with a focus on the inflammatory mediators CRP, IL-6 and ferritin, and their relations to aging in general and Type 2 diabetes in particular. In addition, underlying mechanisms - including those related to gut microbiota and the receptors for AGEs, and the roles AGEs might play in affecting physiologies of the healthy elderly, obese individuals, and diabetics are discussed in regard to any greater susceptibility to COVID-19. Twit Text FOAVip Dietary advanced glycation end-products elicit toxicological effects by disrupting gut microbiome and immune homeostasis ????J Immunotoxicol http://www.kidney.de/pget.php?&tw=1&pmid=34436982 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34436982 #FOAvip English Wikipedia <ref>{{Cite pmid|34436982}}</ref> Dietary advanced glycation end-products elicit toxicological effects by disrupting gut microbiome and immune homeostasis #MMPMID34436982 Chen Y; Guo TL J Immunotoxicol 2021[Jul]; 18 (1): 93-104 PMID34436982show ga The aging immune system is characterized by a low-grade chronic systemic inflammatory state ("inflammaging") marked by elevated serum levels of inflammatory molecules such as interleukin (IL)-6 and C-reactive protein (CRP). These inflammatory markers were also reported to be strong predictors for the development/severity of Type 2 diabetes, obesity, and COVID-19. The levels of these markers have been positively associated with those of advanced glycation end-products (AGEs) generated via non-enzymatic glycation and oxidation of proteins and lipids during normal aging and metabolism. Based on the above observations, it is clinically important to elucidate how dietary AGEs modulate inflammation and might thus increase the risk for aging-exacerbated diseases. The present narrative review discusses the potential pro-inflammatory properties of dietary AGEs with a focus on the inflammatory mediators CRP, IL-6 and ferritin, and their relations to aging in general and Type 2 diabetes in particular. In addition, underlying mechanisms - including those related to gut microbiota and the receptors for AGEs, and the roles AGEs might play in affecting physiologies of the healthy elderly, obese individuals, and diabetics are discussed in regard to any greater susceptibility to COVID-19. |Aging[MESH] |Animals[MESH] |COVID-19/*metabolism[MESH] |Diabetes Mellitus, Type 2/*metabolism[MESH] |Diet[MESH] |Dysbiosis[MESH] |Gastrointestinal Microbiome[MESH] |Glycation End Products, Advanced/immunology/*metabolism[MESH] |Homeostasis[MESH] |Humans[MESH] |Immunity[MESH] |Inflammation Mediators/*metabolism[MESH] |Lipid Metabolism[MESH]Dietary advanced glycation end-products elicit toxicological effects b(epmc).pdf DeepDyve Pubget Overpricing