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10.1186/s40001-021-00557-z http://scihub22266oqcxt.onion/10.1186/s40001-021-00557-z 34433495!8386154!34433495     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Med+Res 2021 ; 26 (1): 98 Nephropedia Template TP {{tp|p=34433495|t=2021. Delayed skin reaction after mRNA-1273 vaccine against SARS-CoV-2: a rare clinical reaction |pdf=|usr=}}{{34433495}} gab.com Text Delayed skin reaction after mRNA-1273 vaccine against SARS-CoV-2: a rare clinical reaction JO: Eur J Med Res http://www.kidney.de/pget.php?&tw=1&pmid=34433495 #FOAvip BACKGROUND: The coronavirus disease 2019 (COVID-19) is associated with a wide clinical spectrum of skin manifestations, including urticarial, vesicular, vasculitic and chilblain-like lesions. Recently, delayed skin reactions have been reported in 1% individuals following mRNA vaccination against SARS-CoV-2. The exact pathophysiology and the risk factors still remain unclear. PATIENTS AND METHODS: 6821 employees and patients were vaccinated at our institutions between February and June 2021. Every patient received two doses of the mRNA-1273 vaccine in our hospitals, and reported back in case of any side effects which were collected in our hospital managed database. RESULTS: Eleven of 6821 vaccinated patients (0.16%) developed delayed skin reactions after either the first or second dose of the mRNA-1273 vaccine against SARS-CoV-2. Eight of 11 patients (73%) developed a rash after the first dose, while in 3/11 (27%), the rash occurred after the second dose. More females (9/11) were affected. Four of 11 patients required antihistamines, with two needing additional topical steroids. All the cutaneous manifestations resolved within 14 days. None of the skin reactions after the first dose of the vaccine prevented the administration of the second dose. There were no long-term cutaneous sequelae in any of the affected individuals. CONCLUSION: Our data suggests that skin reactions after the use of mRNA-1273 vaccine against SARS-CoV-2 are possible, but rare. Further studies need to be done to understand the pathophysiology of these lesions. Twit Text FOAVip Delayed skin reaction after mRNA-1273 vaccine against SARS-CoV-2: a rare clinical reaction ????Eur J Med Res http://www.kidney.de/pget.php?&tw=1&pmid=34433495 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34433495 #FOAvip English Wikipedia <ref>{{Cite pmid|34433495}}</ref> Delayed skin reaction after mRNA-1273 vaccine against SARS-CoV-2: a rare clinical reaction #MMPMID34433495 Hoff NP; Freise NF; Schmidt AG; Firouzi-Memarpuri P; Reifenberger J; Luedde T; Bolke E; Meller S; Homey B; Feldt T; Jensen BEO; Keitel V; Schmidt L; Maas K; Haussmann J; Tamaskovics B; Budach W; Fischer JC; Buhren BA; Knoefel WT; Schneider M; Gerber PA; Pedoto A; Haussinger D; Grebe O; van Griensven M; Braun SA; Salzmann S; Rezazadeh A; Matuschek C Eur J Med Res 2021[Aug]; 26 (1): 98 PMID34433495show ga BACKGROUND: The coronavirus disease 2019 (COVID-19) is associated with a wide clinical spectrum of skin manifestations, including urticarial, vesicular, vasculitic and chilblain-like lesions. Recently, delayed skin reactions have been reported in 1% individuals following mRNA vaccination against SARS-CoV-2. The exact pathophysiology and the risk factors still remain unclear. PATIENTS AND METHODS: 6821 employees and patients were vaccinated at our institutions between February and June 2021. Every patient received two doses of the mRNA-1273 vaccine in our hospitals, and reported back in case of any side effects which were collected in our hospital managed database. RESULTS: Eleven of 6821 vaccinated patients (0.16%) developed delayed skin reactions after either the first or second dose of the mRNA-1273 vaccine against SARS-CoV-2. Eight of 11 patients (73%) developed a rash after the first dose, while in 3/11 (27%), the rash occurred after the second dose. More females (9/11) were affected. Four of 11 patients required antihistamines, with two needing additional topical steroids. All the cutaneous manifestations resolved within 14 days. None of the skin reactions after the first dose of the vaccine prevented the administration of the second dose. There were no long-term cutaneous sequelae in any of the affected individuals. CONCLUSION: Our data suggests that skin reactions after the use of mRNA-1273 vaccine against SARS-CoV-2 are possible, but rare. Further studies need to be done to understand the pathophysiology of these lesions. |2019-nCoV Vaccine mRNA-1273[MESH] |Adult[MESH] |Aged[MESH] |COVID-19 Vaccines/*adverse effects[MESH] |COVID-19/*prevention & control[MESH] |Dermatitis/drug therapy/epidemiology/*etiology[MESH] |Erythema/drug therapy/epidemiology/*etiology[MESH] |Female[MESH] |Histamine Antagonists/therapeutic use[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Steroids/therapeutic use[MESH]Delayed skin reaction after mRNA-1273 vaccine against SARS-CoV-2: a ra(epmc).pdf DeepDyve Pubget Overpricing