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10.1016/j.clinre.2021.101793 http://scihub22266oqcxt.onion/10.1016/j.clinre.2021.101793 34428501!8380064!34428501     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Res+Hepatol+Gastroenterol 2022 ; 46 (2): 101793 Nephropedia Template TP {{tp|p=34428501|t=2022. COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms |pdf=|usr=}}{{34428501}} gab.com Text COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms JO: Clin Res Hepatol Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=34428501 #FOAvip Currently, there have been more than one hundred million confirmed cases of coronavirus disease 2019 (COVID-19), with two million deaths worldwide. This has caused a huge medical burden. Severe COVID-19 patients can experience multi-organ damage, including cardiac injury, kidney injury, and liver injury. About 2.0%-4.9% of COVID-19 cases involve patients with preexisting liver diseases. Additionally, preexisting liver diseases were reported and associated with severity (odds ratio (OR) or risk ratio (RR) = 1.48-1.70) and mortality (OR or RR = 1.08-2.65) among COVID-19 patients. Furthermore, the prevalence of liver injury was 16%-29% in COVID-19 patients. Higher prevalence of liver injury may worsen prognosis in patients (severity: OR or RR = 1.9-2.6; mortality: OR or RR = 1.1-4.0). The mechanisms of this association between liver injury and severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection are complex, including direct cholangiocyte damage induced by SARS-COV-2, cytokine storm, and drug-induced liver injury. In particular, drug-induced liver injury may be the most important reason. This review discusses the epidemiology of COVID-19 and liver dysfunction as well as potential mechanisms underlying the association between COVID-19 and liver dysfunction or other preexisting liver diseases. However, the association between preexisting liver diseases and COVID-19 prognosis and potential mechanisms underlying these associations require further prospective studies. Twit Text FOAVip COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms ????Clin Res Hepatol Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=34428501 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34428501 #FOAvip English Wikipedia <ref>{{Cite pmid|34428501}}</ref> COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms #MMPMID34428501 Du M; Yang S; Liu M; Liu J Clin Res Hepatol Gastroenterol 2022[Feb]; 46 (2): 101793 PMID34428501show ga Currently, there have been more than one hundred million confirmed cases of coronavirus disease 2019 (COVID-19), with two million deaths worldwide. This has caused a huge medical burden. Severe COVID-19 patients can experience multi-organ damage, including cardiac injury, kidney injury, and liver injury. About 2.0%-4.9% of COVID-19 cases involve patients with preexisting liver diseases. Additionally, preexisting liver diseases were reported and associated with severity (odds ratio (OR) or risk ratio (RR) = 1.48-1.70) and mortality (OR or RR = 1.08-2.65) among COVID-19 patients. Furthermore, the prevalence of liver injury was 16%-29% in COVID-19 patients. Higher prevalence of liver injury may worsen prognosis in patients (severity: OR or RR = 1.9-2.6; mortality: OR or RR = 1.1-4.0). The mechanisms of this association between liver injury and severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection are complex, including direct cholangiocyte damage induced by SARS-COV-2, cytokine storm, and drug-induced liver injury. In particular, drug-induced liver injury may be the most important reason. This review discusses the epidemiology of COVID-19 and liver dysfunction as well as potential mechanisms underlying the association between COVID-19 and liver dysfunction or other preexisting liver diseases. However, the association between preexisting liver diseases and COVID-19 prognosis and potential mechanisms underlying these associations require further prospective studies. |*COVID-19 Drug Treatment[MESH] |*COVID-19/complications/epidemiology[MESH] |*Liver Diseases/epidemiology/virology[MESH] |Chemical and Drug Induced Liver Injury/epidemiology[MESH] |Humans[MESH] |Risk Factors[MESH]COVID-19 and liver dysfunction: Epidemiology, association and potentia(epmc).pdf DeepDyve Pubget Overpricing