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10.1016/j.diagmicrobio.2021.115412 http://scihub22266oqcxt.onion/10.1016/j.diagmicrobio.2021.115412 34425450!8377389!34425450     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diagn+Microbiol+Infect+Dis 2021 ; 101 (3): 115412 Nephropedia Template TP {{tp|p=34425450|t=2021. Evaluation of commercial SARS-CoV-2 serological assays in Canadian public health laboratories |pdf=|usr=}}{{34425450}} gab.com Text Evaluation of commercial SARS-CoV-2 serological assays in Canadian public health laboratories JO: Diagn Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=34425450 #FOAvip The COVID-19 pandemic has led to the influx of immunoassays for the detection of antibodies towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the global market. The Canadian Public Health Laboratory Network Serology Task Force undertook a nationwide evaluation of twelve laboratory and 6 point-of-care based commercial serological assays for the detection of SARS-CoV-2 antibodies. We determined that there was considerable variability in the performance of individual tests and that an orthogonal testing algorithm should be prioritized to maximize the accuracy and comparability of results across the country. The manual enzyme immunoassays and point-of-care tests evaluated had lower specificity and increased coefficients of variation compared to automated enzyme immunoassays platforms putting into question their utility for large-scale sero-surveillance. Overall, the data presented here provide a comprehensive approach for applying accurate serological assays for longitudinal sero-surveillance and vaccine trials while informing Canadian public health policy. Twit Text FOAVip Evaluation of commercial SARS-CoV-2 serological assays in Canadian public health laboratories ????Diagn Microbiol Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=34425450 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34425450 #FOAvip English Wikipedia <ref>{{Cite pmid|34425450}}</ref> Evaluation of commercial SARS-CoV-2 serological assays in Canadian public health laboratories #MMPMID34425450 Stein DR; Osiowy C; Gretchen A; Thorlacius L; Fudge D; Lang A; Sekirov I; Morshed M; Levett PN; Tran V; Kus JV; Gubbay J; Mohan V; Charlton C; Kanji JN; Tipples G; Serhir B; Therrien C; Roger M; Jiao L; Zahariadis G; Needle R; Gilbert L; Desnoyers G; Garceau R; Bouhtiauy I; Longtin J; El-Gabalawy N; Dibernardo A; Lindsay LR; Drebot M Diagn Microbiol Infect Dis 2021[Nov]; 101 (3): 115412 PMID34425450show ga The COVID-19 pandemic has led to the influx of immunoassays for the detection of antibodies towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the global market. The Canadian Public Health Laboratory Network Serology Task Force undertook a nationwide evaluation of twelve laboratory and 6 point-of-care based commercial serological assays for the detection of SARS-CoV-2 antibodies. We determined that there was considerable variability in the performance of individual tests and that an orthogonal testing algorithm should be prioritized to maximize the accuracy and comparability of results across the country. The manual enzyme immunoassays and point-of-care tests evaluated had lower specificity and increased coefficients of variation compared to automated enzyme immunoassays platforms putting into question their utility for large-scale sero-surveillance. Overall, the data presented here provide a comprehensive approach for applying accurate serological assays for longitudinal sero-surveillance and vaccine trials while informing Canadian public health policy. |*Public Health[MESH] |Antibodies, Viral/*blood[MESH] |COVID-19/blood/*epidemiology[MESH] |Canada/epidemiology[MESH] |High-Throughput Screening Assays[MESH] |Humans[MESH] |Immunoenzyme Techniques[MESH] |Laboratories/*standards[MESH] |SARS-CoV-2/*immunology/isolation & purification[MESH]Evaluation of commercial SARS-CoV-2 serological assays in Canadian pub(epmc).pdf DeepDyve Pubget Overpricing