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suck abstract from ncbi


10.1016/j.clinimag.2021.08.002

http://scihub22266oqcxt.onion/10.1016/j.clinimag.2021.08.002
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suck abstract from ncbi


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pmid34418873      Clin+Imaging 2021 ; 80 (ä): 262-267
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  • FDG PET/CT imaging features and clinical utility in COVID-19 #MMPMID34418873
  • Yeh R; Elsakka A; Wray R; Johnston RP; Gangai NC; Yarmohammadi H; Schoder H; Pandit-Taskar N
  • Clin Imaging 2021[Dec]; 80 (ä): 262-267 PMID34418873show ga
  • PURPOSE: To determine the imaging findings and potential clinical utility of FDG PET/CT in patients with laboratory-confirmed COVID-19. METHODS: We performed a single institution retrospective review of patients diagnosed with COVID-19 using real time reverse transcription-polymerase chain reaction (RT-PCR) who underwent FDG PET/CT for routine cancer care between March 1, 2020 to April 30, 2020, during the height of the pandemic in New York City, New York, United States. PET/CT scans were retrospectively reviewed for imaging findings suspicious for COVID-19. For positive scans, PET and CT findings were recorded, including location, FDG avidity (SUV(max)) and CT morphology. Patient demographics and COVID-19 specific clinical data were collected and analyzed with respect to PET/CT scan positivity, lung SUV(max), and time interval between PET/CT and RT-PCR. RESULTS: Thirty-one patients (21 males and 10 females, mean age 57 years +/- 16) were evaluated. Thirteen of 31 patients had positive PET/CT scans, yielding a detection rate of 41.9%. Patients with positive scans had significantly higher rates of symptomatic COVID-19 infection (77% vs 28%, p = 0.01) and hospitalizations (46% vs. 0%, p = 0.002) compared to patients with negative scans. Eleven of 13 patients (84.6%) with positive scans had FDG-avid lung findings, with mean lung SUV(max) of 5.36. Six of 13 patients (46.2%) had extrapulmonary findings of FDG-avid thoracic lymph nodes. The detection rate was significantly lower when the scan was performed before RT-PCR versus after RT-PCR (18.8% (n = 3/16) vs. 66.7% (n = 10/15), p = 0.009). Lung SUV(max) was not associated with COVID-19 symptoms, severity, or disease course. CONCLUSION: FDG PET/CT has limited sensitivity for detecting COVID-19 infection. However, a positive PET scan is associated with higher risk of symptomatic infection and hospitalizations, which may be helpful in predicting disease severity.
  • |*COVID-19[MESH]
  • |*Positron Emission Tomography Computed Tomography[MESH]
  • |Female[MESH]
  • |Fluorodeoxyglucose F18[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |New York City[MESH]
  • |Positron-Emission Tomography[MESH]
  • |Radiopharmaceuticals[MESH]
  • |Retrospective Studies[MESH]


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