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10.1002/iub.2546

http://scihub22266oqcxt.onion/10.1002/iub.2546
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34418270!8653061!34418270
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suck abstract from ncbi


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pmid34418270      IUBMB+Life 2021 ; 73 (10): 1198-1204
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  • 2-Deoxy-d-glucose exploits increased glucose metabolism in cancer and viral-infected cells: Relevance to its use in India against SARS-CoV-2 #MMPMID34418270
  • Mesri EA; Lampidis TJ
  • IUBMB Life 2021[Oct]; 73 (10): 1198-1204 PMID34418270show ga
  • Mechanisms discovered to drive increased glucose metabolism in cancer cells are found to be similar to those in viral-infected cells. In this mini review, we summarize the major pathways by which the sugar analog, 2-Deoxy-d-glucose, has been shown to exploit increased glucose metabolism in cancer and how this information applies to viral-infected cells. Moreover, we highlight the relevance of these findings to the emergency approval of 2-Deoxy-d-glucose in India to be used against SARS-CoV-2, the virus responsible for COVID-19.
  • |COVID-19/*metabolism/virology[MESH]
  • |Deoxyglucose/*pharmacology[MESH]
  • |Glucose/*metabolism[MESH]
  • |Humans[MESH]
  • |India[MESH]
  • |Neoplasms/*metabolism[MESH]


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