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10.21873/invivo.12587

http://scihub22266oqcxt.onion/10.21873/invivo.12587
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34410992!8408738!34410992
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suck abstract from ncbi


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pmid34410992      In+Vivo 2021 ; 35 (5): 2947-2949
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  • Nine Cases of SARS-CoV-2-PCR-positive Samples Showed No Increase of Antibodies Against SARS-CoV-2 #MMPMID34410992
  • Kitagawa T; Kobayashi M; Ohta T; Terasaki M; Tsukamoto Y; Takai R; Ishizumi R; Uehara O; Nakagawa K; Akino K; Asaka M; Kuramitsu Y
  • In Vivo 2021[Sep]; 35 (5): 2947-2949 PMID34410992show ga
  • BACKGROUND/AIM: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been affecting Hokkaido, Japan since late February 2020 until present. The aim of this study was to report the relationship between anti-SARS-CoV-2 antibody-positive and SARS-CoV-2 PCR-positive cases by analyzing anti-SARS-CoV-2 antibodies (IgG and total-Ig). PATIENTS AND METHODS: Serum samples were collected from care workers and nurses in two nursing homes and two hospitals which underwent virus outbreak. All people were confirmed to be SARS-CoV-2-positive by RT-qPCR and their sera was analyzed for anti-SARS-CoV-2 antibodies (IgG and total-Ig). RESULTS: Although 34 out of 43 samples (79.1%) showed enough amount of anti-SARS-CoV-2 antibodies, 9 RT-qPCR -positive samples (20.9%) showed absence of anti-SARS-CoV-2 antibodies in their sera. CONCLUSION: The results that 20.9% of RT-qPCR-positive samples with SARS-CoV-2 showed absence of anti-SARS-CoV-2 antibodies provides a possibility that the innate immune reaction could eliminate the virus without activating adaptive immune reaction.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Antibodies, Viral[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G[MESH]


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