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10.1080/07435800.2021.1967376

http://scihub22266oqcxt.onion/10.1080/07435800.2021.1967376
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34409914!ä!34409914

suck abstract from ncbi


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pmid34409914      Endocr+Res 2022 ; 47 (1): 32-38
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  • The Relationship Between Insulin Use And Increased Mortality In Patients With COVID-19 And Diabetes: A Meta-Analysis #MMPMID34409914
  • Wang W; Sun Y; Wang S; Sun Y
  • Endocr Res 2022[Feb]; 47 (1): 32-38 PMID34409914show ga
  • PURPOSE: The purpose of this study is to review observational studies on the effect of insulin use and mortality in patients with COVID-19 and diabetes. METHODS: A systematic literature search was performed using the PubMed, Medline, EMBASE, and Cochrane Library databases. The meta-analysis was performed using a random effects model, and I(2) was applied to evaluate heterogeneity. Sensitivity and subgroup analyses were also performed. RESULTS: Overall, 1,338 patients over six studies were ultimately included. Insulin use was related to a higher risk of death in diabetic patients with COVID-19 compared to those who did not use insulin (odds ratio: 2.59, 95% confidence interval: 1.66-4.05; P < .0001; I(2): 57%). CONCLUSIONS: This meta-analysis revealed a correlation between insulin usage and increased mortality in diabetic patients with COVID-19. These results showed that insulin requirement in patients with COVID-19 and diabetes might indicate a poor prognosis.
  • |*COVID-19[MESH]
  • |*Diabetes Mellitus/drug therapy[MESH]
  • |Humans[MESH]
  • |Insulin[MESH]
  • |Observational Studies as Topic[MESH]


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