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10.1002/cnr2.1506

http://scihub22266oqcxt.onion/10.1002/cnr2.1506
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suck abstract from ncbi


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pmid34405968      Cancer+Rep+(Hoboken) 2022 ; 5 (5): e1506
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  • Psychosocial perspectives among cancer patients during the coronavirus disease 2019 (COVID-19) crisis: An observational longitudinal study #MMPMID34405968
  • Turgeman I; Goshen-Lago T; Waldhorn I; Karov K; Groisman L; Reiner Benaim A; Almog R; Halberthal M; Ben-Aharon I
  • Cancer Rep (Hoboken) 2022[May]; 5 (5): e1506 PMID34405968show ga
  • BACKGROUND: The coronavirus disease 2019 (COVID-19) crisis and consequent changes in medical practice have engendered feelings of distress in diverse populations, potentially adversely affecting the psychological well-being of cancer patients. AIM: The purpose of this observational longitudinal study was to evaluate psychosocial perspectives among patients with cancer on intravenous treatment during the COVID-19 pandemic. METHODS AND RESULTS: The study recruited 164 cancer patients undergoing intravenous anti-neoplastic therapy in a tertiary cancer center. Psychosocial indices were assessed at two points in time, corresponding with the beginning of the first wave of COVID-19 pandemic in Israel (March 2020) and the time of easing of restrictions implemented to curtail spread of infection (May 2020). At Time 1 (T1), elevated COVID-19 distress levels (score 1 and 2 on 5-point scale) were observed in 44% of patients, and associated with pre-existing hypertension and lung disease in multivariate analyses but no demographic or cancer related factors. At Time 2 (T2), 10% had elevated anxiety and 24% depression as indicated by Hospital Anxiety and Depression Scale (HADS-A/D). COVID-19 distress at T1 was related to higher levels of HADS-A at T2 (Spearman 0.33 p < .01), but not HADS-D. Patients with breast cancer expressed greater COVID-19 distress compared with other cancer types (p < .01), while both HADS-A and HADS-D were highest for patients with GI cancer. Patient report of loneliness and decreased support from relatives were factors associated with HADS-A (p = .03 and p < .01, respectively), while HADS-D was not similarly related to the factors evaluated. CONCLUSION: Patients with cancer undergoing intravenous treatment may be vulnerable to acute adverse psychological ramifications of COVID-19, specifically exhibiting high levels of anxiety. These appear unrelated to patient age or disease stage. Those with underlying comorbidities, breast cancer or reduced social support may be at higher risk.
  • |*Breast Neoplasms/epidemiology/therapy[MESH]
  • |*COVID-19/epidemiology[MESH]
  • |Depression/epidemiology/etiology/psychology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Longitudinal Studies[MESH]
  • |Pandemics[MESH]


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