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10.1016/j.amsu.2021.102673 http://scihub22266oqcxt.onion/10.1016/j.amsu.2021.102673 34401147!8359564!34401147     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=34401147&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Ann+Med+Surg+(Lond) 2021 ; 69 (?): 102673 Nephropedia Template TP {{tp|p=34401147|t=2021. Association of serum KL-6 levels on COVID-19 severity: A cross-sectional study design with purposive sampling |pdf=|usr=}}{{34401147}} gab.com Text Association of serum KL-6 levels on COVID-19 severity: A cross-sectional study design with purposive sampling JO: Ann Med Surg (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=34401147 #FOAvip BACKGROUND: The main target of SARS-CoV2 is the alveolar type II (AT2) cells of the lung. SARS-CoV2 evades the innate immune system resulting in the release of proinflammatory cytokines (IL-1beta, IL-6, TNF-alpha) which causes AT2 cell damage. Krebs von den Lungen (KL-6) is a specific biomarker of AT2 cell damage. KL-6 is produced in AT2 cells that are injured/regenerated. OBJECTIVE: Research that discusses the role of KL-6 in COVID-19 is still being debated and not much has been done in Indonesia. METHODS: This study was an analytical study with a prospective design on 75 COVID-19 patients who were treated. Subjects were divided into two large groups according to their degree of severity, 57 subjects with severe degrees and 18 subjects with non-severe degrees. The serum KL-6 levels were measured on days 0 and 6. Data were analyzed using paired t-test and independent t-test for data were normally distributed and Wilcoxon test and Mann Whitney test for data that were not normally distributed. RESULT: In this study, the mean serum KL-6 for day 0 in the severe group was higher than the non-severe group with values of 45.70 U/mL and 44.85 U/mL. On day 6, the mean serum KL-6 in the severe group was lower than that in the non-severe group with values of 41.3 U/mL and 41.95 U/mL. Serum KL-6 in the severe group experienced an even greater decrease than the non-severe group. CONCLUSION: There was no significant association between serum KL-6 values on 0 days in the severity of COVID-19. Twit Text FOAVip Association of serum KL-6 levels on COVID-19 severity: A cross-sectional study design with purposive sampling ????Ann Med Surg (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=34401147 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34401147 #FOAvip English Wikipedia <ref>{{Cite pmid|34401147}}</ref> Association of serum KL-6 levels on COVID-19 severity: A cross-sectional study design with purposive sampling #MMPMID34401147 Suryananda TD; Yudhawati R Ann Med Surg (Lond) 2021[Sep]; 69 (?): 102673 PMID34401147show ga BACKGROUND: The main target of SARS-CoV2 is the alveolar type II (AT2) cells of the lung. SARS-CoV2 evades the innate immune system resulting in the release of proinflammatory cytokines (IL-1beta, IL-6, TNF-alpha) which causes AT2 cell damage. Krebs von den Lungen (KL-6) is a specific biomarker of AT2 cell damage. KL-6 is produced in AT2 cells that are injured/regenerated. OBJECTIVE: Research that discusses the role of KL-6 in COVID-19 is still being debated and not much has been done in Indonesia. METHODS: This study was an analytical study with a prospective design on 75 COVID-19 patients who were treated. Subjects were divided into two large groups according to their degree of severity, 57 subjects with severe degrees and 18 subjects with non-severe degrees. The serum KL-6 levels were measured on days 0 and 6. Data were analyzed using paired t-test and independent t-test for data were normally distributed and Wilcoxon test and Mann Whitney test for data that were not normally distributed. RESULT: In this study, the mean serum KL-6 for day 0 in the severe group was higher than the non-severe group with values of 45.70 U/mL and 44.85 U/mL. On day 6, the mean serum KL-6 in the severe group was lower than that in the non-severe group with values of 41.3 U/mL and 41.95 U/mL. Serum KL-6 in the severe group experienced an even greater decrease than the non-severe group. CONCLUSION: There was no significant association between serum KL-6 values on 0 days in the severity of COVID-19. ?Association of serum KL-6 levels on COVID-19 severity: A cross-section(epmc).pdf DeepDyve Pubget Overpricing