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10.4049/immunohorizons.2100022 http://scihub22266oqcxt.onion/10.4049/immunohorizons.2100022 34398806!8452279!34398806     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunohorizons 2021 ; 5 (6): 466-476 Nephropedia Template TP {{tp|p=34398806|t=2021. Specific COVID-19 Symptoms Correlate with High Antibody Levels against SARS-CoV-2 |pdf=|usr=}}{{34398806}} gab.com Text Specific COVID-19 Symptoms Correlate with High Antibody Levels against SARS-CoV-2 JO: Immunohorizons http://www.kidney.de/pget.php?&tw=1&pmid=34398806 #FOAvip Lasting immunity will be critical for overcoming COVID-19. However, the factors associated with the development of high titers of anti-SARS-CoV-2 Abs and how long those Abs persist remain incompletely defined. In particular, an understanding of the relationship between COVID-19 symptoms and anti-SARS-CoV-2 Abs is limited. To address these unknowns, we quantified serum anti-SARS- CoV-2 Abs in clinically diverse COVID-19 convalescent human subjects 5 wk (n = 113) and 3 mo (n = 79) after symptom resolution with three methods: a novel multiplex assay to quantify IgG against four SARS-CoV-2 Ags, a new SARS-CoV-2 receptor binding domain-angiotensin converting enzyme 2 inhibition assay, and a SARS-CoV-2 neutralizing assay. We then identified clinical and demographic factors, including never-before-assessed COVID-19 symptoms, that consistently correlate with high anti-SARS-CoV-2 Ab levels. We detected anti-SARS-CoV-2 Abs in 98% of COVID-19 convalescent subjects 5 wk after symptom resolution, and Ab levels did not decline at 3 mo. Greater disease severity, older age, male sex, higher body mass index, and higher Charlson Comorbidity Index score correlated with increased anti-SARS-CoV-2 Ab levels. Moreover, we report for the first time (to our knowledge) that COVID-19 symptoms, most consistently fever, body aches, and low appetite, correlate with higher anti-SARS-CoV-2 Ab levels. Our results provide robust and new insights into the development and persistence of anti-SARS-CoV-2 Abs. Twit Text FOAVip Specific COVID-19 Symptoms Correlate with High Antibody Levels against SARS-CoV-2 ????Immunohorizons http://www.kidney.de/pget.php?&tw=1&pmid=34398806 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34398806 #FOAvip English Wikipedia <ref>{{Cite pmid|34398806}}</ref> Specific COVID-19 Symptoms Correlate with High Antibody Levels against SARS-CoV-2 #MMPMID34398806 Amjadi MF; O'Connell SE; Armbrust T; Mergaert AM; Narpala SR; Halfmann PJ; Bashar SJ; Glover CR; Heffron AS; Taylor A; Flach B; O'Connor DH; Kawaoka Y; McDermott AB; Sethi AK; Shelef MA Immunohorizons 2021[Jun]; 5 (6): 466-476 PMID34398806show ga Lasting immunity will be critical for overcoming COVID-19. However, the factors associated with the development of high titers of anti-SARS-CoV-2 Abs and how long those Abs persist remain incompletely defined. In particular, an understanding of the relationship between COVID-19 symptoms and anti-SARS-CoV-2 Abs is limited. To address these unknowns, we quantified serum anti-SARS- CoV-2 Abs in clinically diverse COVID-19 convalescent human subjects 5 wk (n = 113) and 3 mo (n = 79) after symptom resolution with three methods: a novel multiplex assay to quantify IgG against four SARS-CoV-2 Ags, a new SARS-CoV-2 receptor binding domain-angiotensin converting enzyme 2 inhibition assay, and a SARS-CoV-2 neutralizing assay. We then identified clinical and demographic factors, including never-before-assessed COVID-19 symptoms, that consistently correlate with high anti-SARS-CoV-2 Ab levels. We detected anti-SARS-CoV-2 Abs in 98% of COVID-19 convalescent subjects 5 wk after symptom resolution, and Ab levels did not decline at 3 mo. Greater disease severity, older age, male sex, higher body mass index, and higher Charlson Comorbidity Index score correlated with increased anti-SARS-CoV-2 Ab levels. Moreover, we report for the first time (to our knowledge) that COVID-19 symptoms, most consistently fever, body aches, and low appetite, correlate with higher anti-SARS-CoV-2 Ab levels. Our results provide robust and new insights into the development and persistence of anti-SARS-CoV-2 Abs. |Adult[MESH] |Antibodies, Neutralizing/blood/*immunology[MESH] |Antibodies, Viral/blood/*immunology[MESH] |COVID-19/epidemiology/*immunology/virology[MESH] |Cohort Studies[MESH] |Female[MESH] |Hospitalization/statistics & numerical data[MESH] |Humans[MESH] |Immunoglobulin G/blood/*immunology[MESH] |Linear Models[MESH] |Male[MESH] |Middle Aged[MESH] |Multivariate Analysis[MESH] |Pandemics[MESH] |SARS-CoV-2/*immunology/physiology[MESH] |Severity of Illness Index[MESH]Specific COVID-19 Symptoms Correlate with High Antibody Levels against(epmc).pdf DeepDyve Pubget Overpricing