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suck abstract from ncbi


10.1002/pbc.29295

http://scihub22266oqcxt.onion/10.1002/pbc.29295
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34398511!8441639!34398511
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suck abstract from ncbi

pmid34398511      Pediatr+Blood+Cancer 2021 ; 68 (11): e29295
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  • Safety of administration of BNT162b2 mRNA (Pfizer-BioNTech) COVID-19 vaccine in youths and young adults with a history of acute lymphoblastic leukemia and allergy to PEG-asparaginase #MMPMID34398511
  • Mark C; Gupta S; Punnett A; Upton J; Orkin J; Atkinson A; Clarke L; Heisey A; McGovern C; Alexander S
  • Pediatr Blood Cancer 2021[Nov]; 68 (11): e29295 PMID34398511show ga
  • Vaccinationis a critical tool in the prevention of COVID-19 infection for individuals and for communities. The mRNA vaccines contain polyethylene glycol (PEG) as a stabilizer. Currently, in North America, only the BNT162b2 (Pfizer-BioNTech) mRNA vaccine is approved for individuals aged 12-17. Most patients treated with contemporary regimens for acute lymphoblastic leukemia receive PEG-asparaginase (PEG-ASNase) and 10%-30% will develop allergic reactions. Optimizing access and safety for vaccine administration for these patients is critical. This report describes a process developed to support COVID vaccination in a cohort of adolescents and young adults with a history of PEG-ASNase allergy.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Antineoplastic Agents/*adverse effects[MESH]
  • |Asparaginase/*adverse effects[MESH]
  • |BNT162 Vaccine[MESH]
  • |COVID-19 Vaccines/administration & dosage/adverse effects/*therapeutic use[MESH]
  • |COVID-19/complications/*prevention & control[MESH]
  • |Child[MESH]
  • |Drug Hypersensitivity/*complications/etiology[MESH]
  • |Humans[MESH]
  • |Polyethylene Glycols/*adverse effects[MESH]
  • |Precursor Cell Lymphoblastic Leukemia-Lymphoma/*complications/drug therapy[MESH]


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