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10.1097/BOR.0000000000000817

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34397605!8373384!34397605
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suck abstract from ncbi


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pmid34397605      Curr+Opin+Rheumatol 2021 ; 33 (5): 431-445
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  • The role of immunomodulatory medications in the treatment of COVID-19 #MMPMID34397605
  • Sattui SE; Crow MK; Navarro-Millan I
  • Curr Opin Rheumatol 2021[Sep]; 33 (5): 431-445 PMID34397605show ga
  • PURPOSE OF REVIEW: Given the role of inflammation in severe forms of COVID-19, glucocorticoids and disease-modifying antirheumatic drugs (DMARDs) have been assessed as potential COVID-19 therapies. RECENT FINDINGS: Randomized controlled trials (RCTs) have shown that glucocorticoids reduce mortality in severe COVID-19. RCTs of DMARDs have shown mixed results varying on intervention and inclusion criteria. DMARDs, including colchicine or biologic agents, may improve COVID-19 outcomes in specific patient populations. SUMMARY: Glucocorticoids are an effective treatment for the management of severe COVID-19. Further studies are needed to better define the patient populations who could benefit from DMARD use, as well as provide guidance regarding the timing of these interventions.
  • |*Antirheumatic Agents/therapeutic use[MESH]
  • |*Arthritis, Rheumatoid/drug therapy[MESH]
  • |*COVID-19 Drug Treatment[MESH]
  • |Biological Factors/therapeutic use[MESH]
  • |Humans[MESH]


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