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10.1007/s13206-021-00030-3

http://scihub22266oqcxt.onion/10.1007/s13206-021-00030-3
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suck abstract from ncbi


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pmid34394845      Biochip+J 2021 ; 15 (3): 287-295
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  • Electrochemical Microbiosensor for Detecting COVID-19 in a Patient Sample Based on Gold Microcuboids Pattern #MMPMID34394845
  • El-Said WA; Al-Bogami AS; Alshitari W; El-Hady DA; Saleh TS; El-Mokhtar MA; Choi JW
  • Biochip J 2021[]; 15 (3): 287-295 PMID34394845show ga
  • As continues increasing the COVID-19 infections, there is an urgent need for developing fast, simple, selective, and accurate COVID-19 biosensors. A highly uniform gold (Au) microcuboid pattern was used as a microelectrode that allowed monitoring a small analyte. The electrochemical biosensor was used to monitor the COVID-19 S protein within a concentration range from 100 to 5 pmol L(-1); it showed a lower detection limit of 276 fmol L(-1). Finally, the developed COVID-19 sensor was used to detect a positive sample from a human patient obtained through a nasal swab; the results were confirmed using the PCR technique. The results showed that the SWV technique showed high sensitivity towards detecting COVID-19 and good efficiency for detecting COVID-19 in a positive human sample.
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