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10.17305/bjbms.2021.6340

http://scihub22266oqcxt.onion/10.17305/bjbms.2021.6340
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suck abstract from ncbi


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pmid34392826      Bosn+J+Basic+Med+Sci 2022 ; 22 (1): 147-152
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  • Sustained seroprevalence of SARS-CoV-2 antibodies one year after infection: one of the first COVID-19 cluster cases in Bosnia and Herzegovina #MMPMID34392826
  • Susak B; Mikulic V; Lazarevic A; Mikulic I; Arapovic J
  • Bosn J Basic Med Sci 2022[Feb]; 22 (1): 147-152 PMID34392826show ga
  • SARS-CoV-2 (severe acute respiratory syndrome coronavirus type 2) is a novel virus that has been identified as a causal agent of COVID-19, an emergent infectious disease which brought about a new pandemic in the twenty-first century. The immune responses and clinical features of individuals infected with SARS-CoV-2 have not yet been fully described. Thus, in this study, we compare the seroprevalence and define the correlation between symptoms and serological results in the first COVID-19 cluster in the city of Konjic, Bosnia and Herzegovina. Of the total number, 93% of RT-PCR positive participants had positive IgG serology and 75% of them developed symptoms of COVID-19. We found that there was no significant alteration in specific IgG (p = 0.504) antibody levels during the 1-year period after COVID-19. Our results indicate that symptomatic COVID-19 patients have a higher rate of seroconversion (p < 0.01). The IgG seroconversion was correlated with high fever (p = 0.002) and headache (p = 0.007), suggesting that these symptoms could be considered as indicators of a better immune response. This study has demonstrated persistence of sustained levels of specific SARS-CoV-2 antibodies after recovering from COVID-19 infection. However, in order to gain a better insight into the immune response to SARS-CoV-2, further systematic studies should be focused on quality and longevity analyses.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Bosnia and Herzegovina/epidemiology[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]


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